Top Quality Sodium Starch Glycolate (CMS Na)
A superior pharmaceutical excipient for enhanced tablet disintegration and drug delivery.
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Sodium Starch Glycolate
Sodium Starch Glycolate (CMS Na) is a highly effective pharmaceutical excipient that acts as a tablet disintegrant. It is produced through the reaction of starch with chloroacetic acid under alkaline conditions, resulting in a white or almost white, odorless, and hygroscopic powder. This material disperses in water to form a viscous colloidal solution and is insoluble in ethanol or ether. Its primary function is to promote the rapid breakdown of tablets upon contact with moisture, thereby facilitating drug release and absorption.
- Strong water absorption and fast expansion in cold water contribute to its efficacy as a tablet disintegrant.
- This pharmaceutical grade starch derivative can increase the hardness of tablets without negatively impacting their disintegration capabilities, offering a balance in formulation.
- As a hygroscopic pharmaceutical powder, it requires careful handling and storage to maintain its optimal performance.
- Its ability to enhance drug release enhancement makes it a valuable component in various pharmaceutical formulations.
Advantages of Using Sodium Starch Glycolate
Rapid Disintegration
Leveraging its fast expansion disintegrant properties, it ensures tablets break down quickly, facilitating efficient drug release enhancement.
Improved Tablet Integrity
This pharmaceutical excipient helps increase tablet hardness, contributing to better physical integrity during manufacturing and handling, a key aspect for tablet disintegrant performance.
Controlled Swelling
The carefully controlled swelling of this hygroscopic pharmaceutical powder is crucial for its function, ensuring a predictable and effective disintegration process.
Key Applications
Tablet Manufacturing
As a leading tablet disintegrant, it is essential for the effective breakdown of solid dosage forms, ensuring optimal drug bioavailability.
Pharmaceutical Formulations
This pharmaceutical grade starch derivative is widely incorporated into various drug formulations to improve dissolution profiles.
Excipient Sourcing
Ensuring access to high quality excipients like Sodium Starch Glycolate is critical for consistent pharmaceutical product quality.
Drug Delivery Systems
Its ability to promote rapid disintegration contributes to the overall effectiveness of drug delivery system optimization.