Inosine: A Comprehensive Look at its Properties, Applications, and Impact on Cellular Processes
Exploring the essential nucleoside Inosine (CAS 58-63-9), its role in cellular functions, and its implications in research and therapy.
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Inosine
Inosine, identified by CAS number 58-63-9, is a vital nucleoside fundamental to numerous biological processes. Its white crystalline powder appearance and moderate solubility in water make it a versatile compound for various applications. Inosine plays a critical role in RNA synthesis and DNA replication, making it indispensable for cellular growth and division. It is also known to be essential for proper translation in wobble base pairs within transfer RNAs (tRNAs). Beyond its fundamental biological functions, Inosine is a key intermediate in purine metabolism, and research has explored its potential neuroprotective properties and applications in treating autoimmune diseases and Parkinson's disease.
- Investigating Inosine's role in nucleotide metabolism provides insights into how cellular nucleotide imbalances can affect cell growth and proliferation.
- Understanding Inosine's impact on replication stress reveals crucial mechanisms for cellular survival and adaptation.
- Exploring Inosine's cellular processes highlights its fundamental importance in maintaining cellular health and function.
- The study of Inosine's application in cancer research showcases its potential in understanding and targeting disease mechanisms.
Key Advantages
Essential for Cellular Processes
Inosine is fundamental to RNA synthesis and DNA replication, directly supporting cell growth and proliferation, critical aspects of cellular function.
Role in Purine Metabolism
As a key intermediate in purine metabolism, Inosine's pathways are crucial for understanding broader metabolic regulation and potential therapeutic interventions.
Implications in Disease Research
Research into Inosine's cellular processes and its impact on nucleotide imbalance has shed light on its potential roles in neuroprotection and therapeutic strategies for diseases like Parkinson's and autoimmune disorders.
Key Applications
Cell Culture Supplement
Inosine serves as a valuable medium supplement in nucleotide rescue experiments, supporting the growth and study of various cell lines.
Scientific Research Standard
Used as a reference standard in mass spectroscopy, Inosine aids in accurate compound identification and quantification in analytical studies.
Pharmaceutical Intermediate
Its role in purine metabolism and biological signaling makes Inosine an important component in the development of pharmaceutical agents.
Biotechnology Applications
Inosine's unique base-pairing properties are leveraged in biotechnology, particularly in primer design for PCR and in understanding genetic code translation.