Methyl 2-Aminothiazole-5-Carboxylate: A Key Pharmaceutical Intermediate for Dasatinib Synthesis
Discover the critical role of this organic compound in creating life-saving cancer treatments.
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Methyl 2-aminothiazole-5-carboxylate
This compound is a cornerstone in advanced chemical synthesis, particularly valued as a key intermediate in the production of Dasatinib, an important medication for treating certain types of leukemia. Its unique chemical structure makes it indispensable for creating complex pharmaceutical molecules, driving innovation in oncology treatments.
- As a methyl 2-aminothiazole-5-carboxylate intermediate, it plays a crucial role in the complex synthesis pathways of Dasatinib, directly contributing to the availability of critical cancer therapies.
- Understanding the detailed organic compound properties, such as its molecular formula C5H6N2O2S and molecular weight of 158.178 g/mol, is essential for efficient laboratory and industrial applications.
- The high purity (assay ≥98.0%) and specific melting point (184-186°C) of this chemical intermediate ensure reliability and efficacy in pharmaceutical manufacturing processes, meeting stringent industry standards.
- Its utility as a precursor for heterocyclic synthesis highlights its broader importance beyond pharmaceuticals, enabling the creation of diverse functional materials and compounds.
Advantages Provided by the Product
Enhanced Purity for Pharmaceutical Use
Ensuring an assay of ≥98.0%, this intermediate guarantees the high quality required for pharmaceutical applications, minimizing impurities in the final drug product. This commitment to quality is vital for therapeutic efficacy.
Critical for Dasatinib Synthesis
Its role as a key methyl 2-aminothiazole-5-carboxylate intermediate makes it an indispensable component in the multi-step synthesis of Dasatinib, a vital drug for treating chronic myelogenous leukemia and acute lymphoblastic leukemia.
Versatile Chemical Reactivity
The presence of amino and ester groups on the thiazole ring allows for diverse reactions, making it a versatile building block in organic synthesis for various complex molecules.
Key Applications
Pharmaceutical Intermediate
This compound is most recognized for its critical function as an intermediate in the synthesis of Dasatinib, a targeted therapy for specific types of leukemia. Its reliability supports the consistent production of this life-saving medication.
Organic Synthesis
Beyond pharmaceuticals, its structure featuring both an amino group and a carboxylate ester makes it a versatile reagent for various organic synthesis reactions, enabling the creation of novel compounds.
Chemical Research and Development
Researchers leverage its unique properties for exploring new chemical entities and synthetic routes, contributing to advancements in medicinal chemistry and materials science.
Heterocyclic Compound Manufacturing
As a precursor for heterocyclic synthesis, it is valuable for developing compounds with diverse applications, including but not limited to pharmaceuticals and agrochemicals.