N-Boc-Ethanolamine (CAS: 26690-80-2): A Key Intermediate for Advanced Synthesis
Discover the versatility of N-Boc-ethanolamine, a crucial building block for modern organic chemistry and drug development.
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N-Boc-Ethanolamine
N-Boc-ethanolamine, identified by CAS number 26690-80-2, is a pivotal organic compound valued for its dual functionality and the presence of a tert-butoxycarbonyl (Boc) protecting group. This makes it an indispensable reagent in various advanced chemical transformations. Its structure allows for selective reactions, offering chemists precise control in complex synthesis pathways.
- Facilitating Suzuki Reactions: Explore how N-Boc-ethanolamine serves as a key reagent in facilitating Suzuki coupling reactions, a cornerstone of modern organic synthesis.
- Amine Protection in Synthesis: Understand the critical role of Boc-Glycinol in protecting amine functionalities during multi-step organic synthesis, ensuring reaction integrity.
- Versatile Difunctional Reagent: Learn about the utility of tert-Butyl N-(2-hydroxyethyl)carbamate as a difunctional reagent, enabling the construction of complex molecular architectures.
- Drug Discovery Applications: Discover the importance of N-(tert-Butoxycarbonyl)ethanolamine in drug discovery pipelines, where its controlled reactivity aids in the synthesis of potential therapeutic agents.
Key Advantages Offered
Enhanced Synthesis Control
The Boc protecting group on N-Boc-ethanolamine offers excellent control over amine reactivity, crucial for achieving high yields in complex synthetic routes and avoiding unwanted side reactions.
Broad Chemical Compatibility
This compound exhibits good solubility in common organic solvents and is compatible with a wide range of reaction conditions, making it a flexible choice for various synthetic strategies.
Strategic Intermediate for Pharmaceuticals
Leverage the chemical properties of N-Boc-ethanolamine for the synthesis of phosphatidyl ethanolamines and other complex molecules, vital for pharmaceutical research and development.
Key Applications
Organic Synthesis
As a versatile building block, N-Boc-ethanolamine is extensively used in the synthesis of various organic compounds, including complex molecules and specialty chemicals.
Peptide Synthesis
The Boc protecting group is a standard in peptide synthesis, and N-Boc-ethanolamine, or Boc-Glycinol, is utilized for incorporating specific amino acid residues with protected amine functionalities.
Drug Discovery
This compound serves as a critical intermediate in the synthesis of new drug candidates, enabling chemists to build intricate molecular structures with precision.
PROTAC Synthesis
The PEG-based linker characteristic of Boc-NH-PEG1-OH makes it a valuable component in the synthesis of PROTACs, a growing field in targeted protein degradation.