Procarbazine Hydrochloride: Properties, Applications, and Safe Handling
An in-depth look at this vital antineoplastic agent, its uses, and critical precautions for researchers.
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Procarbazine Hydrochloride
Procarbazine hydrochloride is a critical antineoplastic chemotherapy drug, recognized for its role in treating specific cancers such as Hodgkin's lymphoma and certain brain cancers. Its mechanism of action involves acting as an alkylating agent, which interferes with DNA replication, thereby inhibiting the growth and proliferation of cancer cells. Additionally, it possesses monoamine oxidase (MAO) inhibitory properties, which can influence the metabolism of certain neurotransmitters and requires careful consideration of drug and food interactions.
- Explore the detailed properties of Procarbazine Hydrochloride, including its CAS 366-70-1, to understand its chemical behavior and solubility in various solvents like DMSO and water.
- Understand the critical drug interactions of Procarbazine Hydrochloride, which necessitate caution when combined with other medications and certain foods.
- Learn about the antineoplastic and DNA replication inhibitor mechanisms that make Procarbazine Hydrochloride a key component in cancer treatment regimens.
- Familiarize yourself with the essential precautions for the safe handling and administration of Procarbazine Hydrochloride, emphasizing its medical supervision requirements.
Key Advantages
Effective Antineoplastic Action
As a potent antineoplastic chemotherapy drug, Procarbazine Hydrochloride plays a crucial role in combating various forms of cancer, particularly Hodgkin's lymphoma, by targeting rapidly dividing cells.
Dual Mechanism of Action
Its dual function as an alkylating agent and an MAO inhibitor provides a comprehensive approach to cancer therapy, offering multifaceted benefits in treatment protocols.
Extensive Research Applications
The well-documented properties and mechanisms make Procarbazine Hydrochloride a valuable compound for scientific research, particularly in oncology and drug interaction studies.
Key Applications
Cancer Treatment
Used as an antineoplastic agent in combination therapy for Hodgkin's lymphoma and certain brain cancers, highlighting its significance in oncology.
Pharmacological Research
Serves as a key compound in research exploring drug interactions, chemotherapy mechanisms, and the development of new anti-cancer therapies.
DNA Replication Inhibition Studies
Its role in inhibiting DNA replication makes it a valuable tool for understanding cellular processes and the impact of cytotoxic agents.
MAO Inhibition Research
Investigated for its monoamine oxidase inhibitory effects, contributing to research in neurochemistry and the management of conditions influenced by MAO activity.