Crospovidone XL-10: A Key Ingredient for Enhanced Formulations
Discover the power of Crospovidone XL-10 in pharmaceuticals, cosmetics, and beyond.
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Crospovidone XL-10
Crospovidone XL-10 is a highly cross-linked derivative of polyvinylpyrrolidone (PVP), renowned for its excellent swelling and disintegrant properties. Its insoluble nature in water and common solvents, coupled with rapid water absorption, makes it an ideal choice for formulations requiring efficient disintegration and drug release.
- Benefit from rapid disintegration: Crospovidone XL-10 acts as a superdisintegrant, significantly reducing tablet disintegration times, which is crucial for achieving effective drug solubility.
- Enhance drug solubility: This crospovidone variant is an effective dissolution promoter, greatly improving the solubility of poorly water-soluble drugs in solid preparations.
- Leverage its hygroscopic nature: The water-attracting properties of this hygroscopic powder are key to its swelling capabilities, facilitating fluid absorption into tablets.
- Utilize its versatility: From pharmaceutical tablets and capsules to toothpaste and beverage stabilization, its applications are diverse, showcasing its broad utility as a pharmaceutical excipient.
Key Advantages Offered
Superior Disintegration Properties
As a key crospovidone benefit, it ensures rapid and efficient disintegration of solid dosage forms, leading to faster drug release and improved therapeutic outcomes.
Enhanced Bioavailability
By acting as a dissolution promoter, this cross-linked polyvinylpyrrolidone significantly boosts the solubility of APIs, thereby enhancing overall bioavailability.
Broad Application Spectrum
The utility of insoluble PVP extends beyond pharmaceuticals, serving as a stabilizer in beverages and an active ingredient in personal care products like toothpaste.
Key Applications
Pharmaceutical Formulations
Utilized as a superdisintegrant and dissolution promoter in tablets and capsules for faster drug release and improved bioavailability, a critical aspect of oral dosage forms.
Personal Care Products
Incorporated into toothpaste formulations to act as a moisturizer and provide anti-inflammatory benefits, improving oral hygiene products.
Beverage Stabilization
Serves as a stabilizer and clarifier in beverages such as beer and wine, removing polyphenols and tannins to improve clarity and stability.
General Industrial Use
Its unique properties make it suitable for various industrial applications, including as an adsorbent for purification processes.
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