Unlocking Neuroprotection: A Deep Dive into (R)-3-Amino-4-(3-chlorophenyl)butanoic Acid Hydrochloride
Explore the synthesis, applications, and neuroprotective potential of this key chiral amino acid derivative.
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(R)-3-Amino-4-(3-chlorophenyl)butanoic acid hydrochloride
This chiral beta-amino acid derivative is a crucial compound in pharmaceutical research, particularly for its potential in neuroscience and drug development for neurodegenerative diseases. Its unique structure allows for specific interactions with biological targets, making it invaluable for investigative studies.
- Discover the intricacies of R-3-Amino-4-(3-chlorophenyl)butanoic acid hydrochloride synthesis, a vital step in drug discovery.
- Investigate the neuroprotective potential of chiral amino acids and their role in combating neurological disorders.
- Learn how the inhibition of kynurenine-3-hydroxylase offers new therapeutic avenues.
- Understand the impact of modulating the glutamatergic system in neuroscience for cognitive function enhancement.
Key Advantages
Advanced Synthesis Methods
Explore sophisticated techniques like rhodium-catalyzed hydrogenation and organocatalytic Michael addition for efficient and pure synthesis, crucial for drug development for neurodegenerative diseases.
Therapeutic Potential
The compound shows promise in treating conditions like Alzheimer's and Huntington's chorea by inhibiting key enzymes, highlighting its importance in neuroscience research.
Research Versatility
Serves as an essential research tool for pharmacologists studying neurotransmission and synaptic plasticity, contributing to a deeper understanding of neurological mechanisms.
Key Applications
Pharmaceutical Intermediate Production
Essential building block for synthesizing advanced pharmaceutical compounds, particularly those targeting central nervous system disorders. Aids in drug development for neurodegenerative diseases.
Neuroscience Research Tool
Used in studies to understand synaptic transmission and plasticity, contributing to advancements in treating cognitive impairments and neurological conditions.
Enzyme Inhibition Studies
Key for research into enzyme inhibition, such as KYN-3-OHase, offering insights into metabolic pathways relevant to diseases like Parkinson's.
Chiral Chemistry Development
Provides a platform for exploring chiral synthesis and the impact of stereochemistry on biological activity, vital for R-3-Amino-4-(3-chlorophenyl)butanoic acid hydrochloride synthesis.