Exploring 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine Hydrochloride
A deep dive into a crucial building block for pharmaceutical innovation and drug development.
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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine Hydrochloride
This compound is a critical intermediate in the synthesis of various pharmaceutical compounds, most notably the anti-hypertensive drug Doxazosin. Its structure, featuring an N-acylalkylenediamine moiety, is vital for molecular interactions during drug synthesis. Understanding its properties is key for efficient pharmaceutical intermediate synthesis.
- Synthesis of 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride typically involves piperazine and ethyl 1,4-benzodioxan-2-carboxylate, making it a key compound in Doxazosin synthesis pathway.
- The compound's role as a pharmaceutical building block is underscored by its application in creating complex drug molecules.
- Its interaction with alpha-1 adrenoceptors positions it as a relevant compound for research into conditions managed by alpha-1 adrenoceptor ligands.
- The slightly soluble nature in DMSO and storage requirements under inert gas highlight specific handling protocols for this piperazine derivative synthesis.
Advantages Offered by This Product
Versatile Pharmaceutical Intermediate
As a key pharmaceutical intermediate, this compound significantly streamlines the synthesis of complex active pharmaceutical ingredients (APIs), contributing to faster drug development cycles.
Essential for Anti-Hypertensive Drugs
Its direct role in the synthesis of drugs like Doxazosin makes it indispensable for the production of medications treating cardiovascular conditions, supporting crucial medicinal chemistry research.
Facilitates Advanced Synthesis
The unique structural features of this compound make it an excellent advanced organic building block, enabling chemists to explore novel molecular architectures and functionalities.
Key Applications
Pharmaceutical Synthesis
Serves as a critical intermediate in the creation of various APIs, particularly anti-hypertensive drugs, underscoring its importance in the pharmaceutical intermediates synthesis field.
Medicinal Chemistry Research
Used in laboratories to investigate new drug candidates and understand receptor interactions, leveraging its properties as a piperazine derivative synthesis component.
Drug Discovery
A fundamental building block for discovering and developing new therapeutic agents targeting conditions influenced by alpha-1 adrenoceptors.
Chemical Research
Its well-defined properties and reactivity make it a valuable tool for exploring novel synthetic routes and developing advanced organic synthesis techniques.
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