Investigating BMP Type I Receptor Inhibition with 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Explore the precise mechanisms of BMP signaling modulation for advanced biomedical research.
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4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
This compound is a highly potent and selective inhibitor of Bone Morphogenetic Protein (BMP) type I receptors, particularly ALK2 and ALK3, with significant implications for various research areas including bone development, stem cell biology, and cancer research. Its ability to block BMP-mediated signaling pathways makes it an invaluable tool for dissecting cellular processes influenced by BMPs.
- Discover the critical role of BMP type I receptor inhibition in modulating stem cell differentiation pathways, offering new avenues for regenerative medicine.
- Leverage the precision of ALK2 and ALK3 inhibition to investigate complex cellular signaling cascades and their impact on disease progression.
- Utilize this compound as a key tool in bone morphogenetic protein signaling inhibitor research to understand bone formation and related pathologies.
- Explore the therapeutic potential of targeting cancer signaling pathways by understanding the mechanisms inhibited by this molecule.
Advantages Provided by the Product
High Selectivity and Potency
With precise IC50 values for ALK2 and ALK3, this inhibitor ensures targeted modulation of BMP signaling, minimizing off-target effects in your experiments.
Versatile Research Applications
Its efficacy in inhibiting bone formation, regulating stem cell differentiation, and impacting cancer pathways makes it adaptable for diverse research projects.
Advanced Chemical Properties
Characterized by a distinct yellow to orange powder appearance and a stable molecular structure, it is well-suited for laboratory use and storage.
Key Applications
BMP Signaling Pathway Research
Investigate the intricate mechanisms of BMP signaling, critical for developmental biology and disease pathogenesis, by employing this selective inhibitor.
Stem Cell Differentiation Studies
Modulate stem cell fate and differentiation processes, exploring its potential in regenerative medicine and tissue engineering applications.
Oncology and Cancer Research
Uncover the role of BMP signaling in cancer development and progression, utilizing this compound to target relevant pathways.
Bone Development and Disease Modeling
Study bone formation processes and investigate conditions like osteoporosis or fibrodysplasia ossificans progressiva through precise BMP pathway inhibition.