3-(Di-tert-butylphosphino)propane-1-sulfonic Acid: A Versatile Ligand for Palladium-Catalyzed Cross-Coupling Reactions
Enhance your catalytic processes with a highly stable and effective phosphine ligand.
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3-(Di-tert-butylphosphino)propane-1-sulfonic acid
This bifunctional organophosphorus compound, featuring a sterically demanding di-tert-butylphosphine group and a hydrophilic sulfonic acid moiety, is a key enabler in modern organic synthesis. Its unique structure provides excellent stability and solubility, making it an ideal ligand for palladium-catalyzed cross-coupling reactions. As an organic synthesis building block, it facilitates the formation of complex molecules with high efficiency.
- Explore the advantages of using this 3-(Di-tert-butylphosphino)propane-1-sulfonic acid applications in various catalytic transformations, offering unparalleled control and yields.
- Discover how its role as a water soluble phosphine ligand promotes greener reaction conditions and simplifies product isolation.
- Leverage its capability as a recyclable ligand for catalysis, reducing waste and improving the economic viability of chemical processes.
- Understand its significance as a building block for organic synthesis, enabling the construction of intricate molecular architectures.
Key Advantages
Enhanced Catalytic Activity
As a premier palladium catalyzed cross-coupling ligand, it significantly boosts reaction rates and selectivity, leading to improved outcomes in complex chemical syntheses.
Improved Process Sustainability
The compound's properties as an air stable phosphine ligand and its recyclability contribute to more sustainable and environmentally friendly chemical processes.
Versatile Reactivity Profile
Its dual functionality as a ligand and building block makes it a versatile tool for chemists, supporting applications in catalysis in organic chemistry and beyond.
Key Applications
Palladium-Catalyzed Cross-Coupling
This ligand is pivotal for reactions such as Suzuki-Miyaura, Stille, and Sonogashira couplings, enabling efficient formation of C-C bonds. Utilize it as a Suzuki-Miyaura coupling ligand for superior results.
Organic Synthesis
Serves as a crucial intermediate and building block for the synthesis of complex organic molecules, offering precise control over chemical transformations.
Green Chemistry Initiatives
Its water solubility and stability promote the development of greener catalytic systems, aligning with the principles of sustainable chemistry.
Material Science
The unique structural attributes may find applications in the development of novel materials with tailored properties.
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