Cyclopropyl-; 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea; 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropyl-carbamide.

1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea (CAS: 796848-79-8) is a synthetic organic compound with the molecular formula C11H12ClN3O2. It is a white to light yellow crystalline powder with a molecular weight of 251.68 g/mol.

The compound has a wide range of applications in the pharmaceutical industry, particularly in the treatment of cancer. It functions as a potent inhibitor of the enzyme tyrosine kinase, which is involved in the regulation of cell growth and division. As such, 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea is used in the development of targeted therapies for various types of cancer, including breast cancer, lung cancer, and leukemia.

The compound has also been found to have anti-inflammatory properties, making it a potential candidate for the treatment of inflammatory diseases such as rheumatoid arthritis and multiple sclerosis. Additionally, it has been shown to improve insulin sensitivity and glucose uptake, making it a potential treatment for type 2 diabetes.

1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea is typically synthesized by reacting 2-chloro-4-hydroxyaniline with cyclopropyl isocyanate in the presence of a suitable catalyst. The resulting product is then purified through various techniques such as recrystallization and chromatography.

The compound is classified as a hazardous material, with potential health effects including skin irritation, respiratory tract irritation, and eye irritation. As such, appropriate precautions must be taken when handling and storing the substance.

In conclusion, 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea is a valuable compound with a range of applications in the pharmaceutical industry. Its ability to inhibit tyrosine kinase makes it a promising candidate for the development of targeted cancer therapies, while its anti-inflammatory and anti-diabetic properties make it a potential treatment for a range of other diseases. However, given its hazardous nature, appropriate precautions must be taken when working with the compound.

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