Have you heard of Z-TRP-OME? It is a chemical compound with the CAS number 2717-76-2 and English name (S)-methyl 2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate, but it is also known by other names such as Cbz-L-Tryptophan-methyl ester or N-carbobenzyloxy-L-tryptophan methyl ester. This chemical compound is produced by Ningbo Inno Pharmchem Co., Ltd., a reputable manufacturer of fine chemicals and pharmaceutical intermediates.
Z-TRP-OME is a white to off-white powder that is soluble in organic solvents such as methanol and ethanol. It is commonly used as a reactant or starting material in the synthesis of various pharmaceuticals, such as anti-cancer drugs and anti-depressants. Its high purity and consistent quality make it a popular choice among researchers and manufacturers.
One of the key advantages of Z-TRP-OME is its synthetic route, which has been thoroughly analyzed for feasibility by Ningbo Inno Pharmchem Co., Ltd. The manufacturer has invested significant resources in developing and optimizing the synthetic route to ensure maximum efficiency, yield, and quality. This has resulted in a streamlined process that minimizes waste and reduces production costs, while maintaining high standards of quality control.
The synthetic route of Z-TRP-OME starts with the reaction of L-tryptophan with a reagent such as di-tert-butyl dicarbonate (Boc2O) or benzyloxycarbonyl chloride (Cbz-Cl) to form the corresponding protected amino acid, N-Boc-L-tryptophan or N-Cbz-L-tryptophan. This protected amino acid is then reacted with methyl chloroformate (MeOCOCl) or methyl iodide (MeI) to form the corresponding methyl ester, N-Boc-L-tryptophan methyl ester or N-Cbz-L-tryptophan methyl ester.
The final step involves the deprotection of the benzyloxycarbonyl (Cbz) or Boc protecting group to yield Z-TRP-OME. This can be achieved by using a suitable reagent such as trifluoroacetic acid (TFA) or hydrogen fluoride (HF), followed by purification and isolation of the product.
The feasibility analysis of this synthetic route has shown that it is a cost-effective and reliable method for producing Z-TRP-OME in large quantities. The high yield and purity of the product, combined with the efficient use of resources, make it an attractive option for researchers and manufacturers in the pharmaceutical industry.
In addition to its synthetic route, Z-TRP-OME has several other advantages that make it a valuable compound for pharmaceutical applications. For example, it has a unique chemical structure that can be modified to produce different derivatives with varying biological activities. This versatility allows researchers to tailor the compound to specific therapeutic targets and optimize its pharmacological properties.
Furthermore, Z-TRP-OME is readily available from Ningbo Inno Pharmchem Co., Ltd., which offers it in various quantities and grades to suit different needs. The manufacturer also provides technical support and custom synthesis services to help customers achieve their research and development goals.
Overall, Z-TRP-OME is a promising compound with a well-established synthetic route and a range of beneficial properties for pharmaceutical applications. Its availability from a reputable manufacturer, combined with its versatility and cost-effectiveness, make it a compelling choice for researchers and manufacturers looking for a high-quality starting material for drug discovery and development.
