4-Chloro-3-(trifluoromethyl)phenyl isocyanate

Molecular Formula: C8H3ClF3NO
Molecular Weight:   221.56400

Physical and Chemical Properties:
Density: 1.4 g/cm3
Boiling point: 86-90 °C14 mm Hg(lit.)
Melting point: 40-42 °C(lit.)
Flash point: 211 °F
Refractive index: 1.487

Specification:
Appearance:  white crystalline
Purity:≥98.0%
water content:≤0.5%
Impurity A≤0.15%
Impurity B≤1.0%
Other single impurity≤0.5%
Total impurities≤2.0%

Packing:
 25kg  cardboard drum or according to customer specified requirements
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Application: 
4-Chloro-3-(trifluoromethyl)phenyl isocyanate is used as a reagent to synthesize pyrimidinylaminobenzene derivatives, compounds that have antiproliferative activity against melanoma cell lines. 4-Chloro-3-(trifluoromethyl)phenyl isocyanate is also used to synthesize α-thymidine analogues that act as antimalarial agents.Intermediates of Sorafenib tosylate CAS:475207-59-1.

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