Product details
Cyclopentyl methyl ether_5614-37-9

Cyclopentyl methyl ether

  • CAS:


  • English:

    Cyclopentyl methyl ether

  • Synonym:

    Cyclopentyl Methyl Ether
    Cyclopentyl Methyl Ether CPME
    methyl cyclopentyl ether


Product Name: Cyclopentyl methyl ether
CAS: 5614-37-9
Cyclopentyl Methyl Ether
Cyclopentyl Methyl Ether CPME
methyl cyclopentyl ether
Density 0.86
Boiling Point 106 ºC
Melting Point -140ºC
Molecular Formula C6H12O
Molecular Weight 100.159
Flash Point 6.5±14.2 °C
Appearance: Colorless clear liquid
Identification by GC: The retention time of major peak in sample solution should correspond with that of standard solution as obtained in the 
Water content≤300ppm
Methanol content (ppm)≤50
Odor: A slight characteristic odor
We also supply 2-Methyltetrahydrofuran CAS: 96-47-9 for more info please visit
Cyclopentyl methyl ether is a new environmentally friendly high performance hydrophobic ether solvent, referred to as CPME, which can replace ether solvents such as tetrahydrofuran, methyltetrahydrofuran, methyl tert-butyl ether and dioxane. As a reaction solvent, it can be used for a format reaction, a coupling reaction, a coupling amination reaction, a metal reduction reaction, a Lewis acid reaction, and a Friedel-Crafts reaction. It is also used in extraction, crystallization, surface treatment and polymerization processes.
CPME (cyclopentyl methyl ether) is a new generation of hydrophobic ether solvent. It has excellent properties such as low toxicity, anti-oxidation and anti-explosion, wide temperature and fluidity, and azeotropy with water. It can be widely used as a substitute for THF. 2-MeTHF, diethyl ether, diisopropyl ether, methyl tert-butyl ether, dioxane and other ether solvents can also be used in pharmaceuticals and chemicals instead of halogenated hydrocarbons, ethyl acetate, toluene and other conventional solvents. Industry, materials industry (diluent) and electronics industry (detergent). Based on EHS requirements, CPME has been widely recognized in countries such as Europe and the United States and requires a gradual replacement of the original solvent system in production.
High water repellency
Because it is easy to separate from water and easy to recover from water, it can reduce the amount of waste liquid and waste water.
It can be used in all processes such as reaction, extraction, crystallization, etc., so that one-pot synthesis of the reaction can be carried out.
Easy to dry
Since it can azeotrope with water, azeotropic dehydration can be performed.
With molecular sieves, 25 ppm of water can be dried overnight.
a wide range of liquid states
From low temperature to high temperature, it can be used in a wide temperature range, so the reaction rate can be increased by increasing the reaction temperature, or can be used under low temperature reaction conditions.
Low latent heat of evaporation
Distillation recovery is possible with a small amount of energy.
Not easy to form peroxide
The generated peroxide has a relatively small amount of heat dissipation.
 Smaller explosion range
 Stable to acids and bases
Reaction solvent
Grignard reaction, Suzuki coupling reaction, Buchwald amination, metal reduction (NaBH4, LHA reduction, i-Bu2, AlH reduction), reaction using n-BuLi, reaction using Lewis acid, Friedel-Crafts reaction Wait
Extraction solvent
Recrystallization solvent
Polymer solvent
Coating solvent such as resin

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