Product Name: Remdesivir
Synonym: Remdesivir; GS-5734; GS 5734; GS5734, Prodrug of GS-441524; Prodrug of GS441524; Prodrug of GS441524;
CAS#: 1809249-37-3
Chemical Formula: C28H36N5O8P
Exact Mass: 601.2301
Molecular Weight: 601.5968
IUPAC/Chemical Name: 2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Application:
Remdesivir has been found to show reasonable antiviral activity against more distantly related viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, and MERS-coronavirus and Coronavirus. GS-5734 was rapidly pushed through clinical trials due to the 2013–2016 West African Ebola virus epidemic crisis.
Gilead Sciences has recently confirmed that it is demonstrating whether the experimental Ebola drug Remdesivir may cause a fight against a new coronavirus (2019-nCoV) emerging in China. The company said that "active discussions are underway with researchers and clinicians in the United States and China about the potential use of Remdesivir in therapy."
Remdesivir, also known as GS-5734, is an experimental RNA polymerase inhibitor developed by Gilead Sciences in 2014 in collaboration with the Centers for Disease Control and Prevention (CDC) and the U.S. Army Medical Institute for Infectious Diseases Anthony Fossie, director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (NIH), stated in a comment on JAMA Network that SARS-CoV and MERS-CoV are being used as prototypes to develop treatment strategies for 2019-nCoV. "Broad-spectrum antivirals, such as Remdesivir, lopinavir / ritonavir and interferon, have shown promise against MERS-CoV in animal models and are evaluating their activity against 2019-nCoV," he said.
Our team is proficient in new route design and route optimization. With the skillful skills to solve problems and the high success rate of the project, we have the ability to provide our customers with the following high quality chemical custom synthesis services.We are specialists in chiral chemistry using both chemocatalysis and biocatalysis technologies, but also have practical operating experience over a wide range of modern synthetic reactions.With an international vision, rich management experience, professional R & D team and integrity and rigorous professionalism, we are committed to providing customers with the highest quality products and services.Dozens of reaction types such as chiral synthesis and resolution, oxidation, reduction, condensation, nitrosation, bromination.The company's production base is equipped with enamel reactors from 50L to 5000L, stainless steel ultra-low temperature reactors and conventional separation and drying equipment.
Are you looking for China or India manufacturers of Remdesivir CAS:1809249-37-3, Remdesivir intermediates factory or Remdesivir APIs supplier? Where can buy Remdesivir APIs or if you want to know the price market of Remdesivir APIs? Welcome to contact us for Remdesivir COA or MSDS.
