CAS No: 302-79-4
Product Name: Tretinoin
Other Name:
Tretinoin
Vitamin A Acid
all-trans-retinoic acid
all-trans-β-Retinoic acid
(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid
Density: 1.0±0.1 g/cm3
Boiling Point: 462.8±14.0 °C at 760 mmHg
Melting Point: 179-184ºC
Molecular Formula: C20H28O2
Molecular Weight: 300.435
Flash Point: 350.6±11.0 °C
Exact Mass: 300.208923
PSA: 37.30000
LogP: 6.83
Vapour Pressure: 0.0±2.5 mmHg at 25°C
Index of Refraction: 1.556
Storage condition: 2-8°C
Stability: Store Dry in Freezer at -20°C for up to 1 year; in Solution at -20°C for up to 3 Months.
Water Solubility: insoluble
Specification
Assay HPLC: 98.0% - 102.0%
Appearance: Fine yellow crystal powder
Odor: Characteristic
IR Identification: Past the test
UV Identification: Past the test
Solubility: Practically insoluble in water; Soluble in methylene chloride; Slightly soluble in 96% ethanol
Melting Point: Around 182 °C
Particle Size: 100% pass 110mesh
Loss on Drying: ≤0.50%
Sulfated ash: ≤0.10%
Heavy Metals: ≤20ppm
Related Substances
Impurity A: ≤0.50%
Unspecified Impurities: ≤0.20%
Total Impurities: ≤1.00%
Residue on Ignition: ≤0.10%
Application
Topical retinoids have a strong pharmacological effect when applied topically to the skin. Topical retinoids can improve the skin aging due to sun exposure. This product has significant curative effects on various skin diseases such as acne, ichthyosis, pityriasis furuncle, and common warts. This product can be used as an adjuvant treatment for psoriasis. Can eliminate fine wrinkles, reduce the roughness of the skin, reduce pigmentation, and make the skin ruddy. This product can be used as a pharmaceutical intermediate.
Package: 25kg/drum, can also be designed according to customer requirements.
Storage: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
We have leading technology and rich synthesis experience, and our professional R&D team is currently in the leading position in China.It is a high-tech enterprise integrating R&D, production and sales of APIs, pharmaceutical intermediates, fine chemicals and special catalysts.Has a group of experienced researchers in the field of organic synthetic chemistry, with the ability to solve problems and troubleshoot.Our company has a complete production service chain of grams-kg-ton.Synthesis of reference compounds, intermediates, drug candidates, impurities and metabolites for customers with a range of milligrams to kilograms (including GMP quality).
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