The Role of Aztreonam in Studying Beta-Lactamase Resistance
At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing the scientific community with essential tools for groundbreaking research. Aztreonam (CAS 78110-38-0) stands out as a critical chemical compound, particularly for its role in understanding bacterial resistance to beta-lactam antibiotics. Its unique structural features lend it stability against many of the enzymes that render other beta-lactams ineffective.
Beta-lactamases are enzymes produced by bacteria that hydrolyze the beta-lactam ring, the core structure of antibiotics like penicillins and cephalosporins, rendering them inactive. This is a primary mechanism by which bacteria develop resistance. Aztreonam, as a monobactam, possesses a modified structure that significantly enhances its resistance to degradation by a wide array of these beta-lactamases. This characteristic makes it an invaluable asset for researchers seeking to study the efficacy of antibiotics in the presence of resistance factors.
Researchers frequently utilize Aztreonam in laboratory settings to investigate the specific mechanisms of beta-lactamase production and function. By observing how bacteria, or isolated beta-lactamase enzymes, interact with Aztreonam, scientists can glean critical information about the enzymes' structures, their substrate specificities, and how these enzymes evolve. This knowledge is fundamental for developing new antimicrobial agents or strategies that can overcome existing resistance mechanisms.
The ability to purchase Aztreonam of high purity from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for the accuracy of these studies. The price of Aztreonam reflects its specialized synthesis and its critical role in advancing our comprehension of infectious diseases and antibiotic resistance. Researchers often seek out specific buy options for compounds that enable detailed investigation into bacterial defenses.
In conclusion, Aztreonam's inherent stability against beta-lactamases positions it as a vital research chemical. Its utility in studying the complex interplay between antibiotics and bacterial resistance mechanisms is indispensable for the ongoing effort to develop effective treatments against evolving pathogens.
Perspectives & Insights
Chem Catalyst Pro
“In conclusion, Aztreonam's inherent stability against beta-lactamases positions it as a vital research chemical.”
Agile Thinker 7
“Its utility in studying the complex interplay between antibiotics and bacterial resistance mechanisms is indispensable for the ongoing effort to develop effective treatments against evolving pathogens.”
Logic Spark 24
“, we are committed to providing the scientific community with essential tools for groundbreaking research.”