Valdecoxib (CAS 181695-72-7) presents a distinct set of chemical properties that define its utility and handling. Typically appearing as a white solid, its physical form is consistent with many pharmaceutical intermediates and active pharmaceutical ingredients. Its solubility profile is also noteworthy; while relatively insoluble in neutral water, it exhibits solubility in methanol and ethanol, and is freely soluble in organic solvents and alkaline aqueous solutions. These characteristics are crucial for formulators and chemists working with the compound, influencing everything from synthesis purification to final dosage form development.

As a selective COX-2 inhibitor, Valdecoxib's primary application in medicine relates to its anti-inflammatory, analgesic, and antipyretic effects. Historically, it was developed to treat symptoms associated with conditions like osteoarthritis and rheumatoid arthritis, as well as primary dysmenorrhea. Its mechanism of action, focusing on reducing prostaglandin synthesis through COX-2 inhibition, makes it a potent tool for managing pain and inflammation. For those looking to buy Valdecoxib, understanding these applications is key to its proper utilization.

Beyond its direct medicinal uses, Valdecoxib is extensively utilized as a pharmaceutical intermediate. This means it serves as a foundational chemical building block in the synthesis of other, more complex pharmaceutical compounds. This role is critical in drug discovery and development, enabling the creation of new therapeutic agents with targeted actions. China-based suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., offer Valdecoxib with high purity (99% MIN assay) and adherence to various pharmacopeial standards (USP/BP/EP/FCC), making them valuable partners for companies engaged in pharmaceutical research and manufacturing.

The availability of Valdecoxib through reliable suppliers with competitive pricing and online purchase support simplifies the procurement process for research institutions and manufacturing facilities worldwide. By focusing on the precise chemical properties and established applications of Valdecoxib, the pharmaceutical industry can continue to innovate and provide effective treatments for patients suffering from pain and inflammatory conditions.