At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on offering a comprehensive understanding of the chemical compounds we supply. 2-Chloromethyl-4-Methylquinazoline is a prime example of a versatile chemical intermediate whose synthesis and properties are of great interest to researchers in medicinal chemistry and agrochemical development. Understanding its creation and characteristics is key to unlocking its full potential.

The synthesis of 2-Chloromethyl-4-Methylquinazoline often involves established organic chemistry methodologies. One common route involves the reaction of 1-(2-amino-phenyl)-ethanone with HCl gas under anhydrous conditions in the presence of chloro acetonitrile. This process yields the desired 2-chloromethyl-4-methyl-quinazoline. Subsequently, this intermediate can be treated with various amine derivatives in the presence of a base to generate a range of substituted quinazoline compounds, which are crucial for pharmaceutical and agrochemical applications. The ability to fine-tune these synthesis pathways allows for the production of specific derivatives tailored to particular research needs.

The chemical properties of 2-Chloromethyl-4-Methylquinazoline, such as its reactivity, solubility, and stability, are well-documented. Its melting point of approximately 61-65 °C and its appearance as a white to off-white powder are important physical characteristics. The presence of the chloromethyl group is the primary driver of its utility in synthesis, facilitating SN2 reactions and enabling the construction of more complex molecular architectures. The high assay, typically exceeding 99%, ensures that the compound is suitable for precise chemical transformations.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers with reliable access to this compound. Whether you are interested in its synthesis, its properties, or its purchase, our team is equipped to provide the necessary information and support. We understand the importance of understanding the journey of a chemical intermediate from synthesis to application, ensuring quality and efficacy at every stage.