The Chemistry and Applications of Paracetamol (Acetaminophen) Powder
Paracetamol, scientifically known as acetaminophen, is a fundamental Active Pharmaceutical Ingredient (API) with a rich history and widespread application in modern medicine. Its chemical structure and properties make it a highly effective analgesic and antipyretic. NINGBO INNO PHARMCHEM CO.,LTD. delves into the chemistry and diverse applications of this critical pharmaceutical raw material.
The chemical identity of paracetamol is characterized by its CAS number 103-90-2 and its molecular formula C8H9NO2. Synthesized through processes often involving the acetylation of p-aminophenol, the resulting compound is a white crystalline powder. Its moderate solubility in hot water and alcohol, and its stability under normal conditions, contribute to its ease of formulation into various pharmaceutical dosage forms.
The primary applications of paracetamol powder lie in its role as an analgesic and antipyretic. It works by inhibiting prostaglandin synthesis in the central nervous system, thereby raising the pain threshold and reducing fever. This makes it a go-to ingredient for medications targeting headaches, muscle pain, toothaches, and fevers. Its mild nature means it can be used by a wide demographic, including children and individuals who cannot tolerate NSAIDs.
Pharmaceutical manufacturers rely on obtaining paracetamol powder that meets stringent purity standards, typically exceeding 99%. This ensures the safety and efficacy of the final drug products. The availability of direct compression (DC) grades of paracetamol powder further simplifies manufacturing processes, enabling efficient production of tablets. Sourcing this acetaminophen raw material online from reputable suppliers is a common practice for pharmaceutical companies worldwide.
Beyond its primary applications, paracetamol also finds use in combination therapies. When paired with other active ingredients, it can enhance pain relief for more severe conditions. The consistent demand for this API underscores its importance in the global pharmaceutical supply chain. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality paracetamol powder, supporting the development and manufacturing of essential medicines.
In conclusion, the chemistry of paracetamol powder, encompassing its structure, synthesis, and properties, directly translates to its vital role in healthcare. As a key analgesic and antipyretic API, its accessibility and reliability are crucial for pharmaceutical success, making it an indispensable component in the fight against pain and fever.
Perspectives & Insights
Future Origin 2025
“The chemical identity of paracetamol is characterized by its CAS number 103-90-2 and its molecular formula C8H9NO2.”
Core Analyst 01
“Synthesized through processes often involving the acetylation of p-aminophenol, the resulting compound is a white crystalline powder.”
Silicon Seeker One
“Its moderate solubility in hot water and alcohol, and its stability under normal conditions, contribute to its ease of formulation into various pharmaceutical dosage forms.”