Citicoline Sodium (CAS No. 33818-15-4) is a key compound known for its significant impact on brain health and cognitive function. This naturally occurring substance acts as an intermediate in the synthesis of phosphatidylcholine, a primary component of cell membranes, and is crucial for neurotransmitter production, particularly acetylcholine. Understanding its properties, appropriate dosage, and safety profile is essential for its effective use.

The typical dosage for Citicoline Sodium as a dietary supplement ranges from 250 mg to 500 mg per day. However, for specific therapeutic applications, dosages can extend up to 2,000 mg per day, as determined by healthcare professionals. Research indicates that Citicoline Sodium is generally well-tolerated, with a low incidence of side effects. When side effects do occur, they are typically mild and may include stomach discomfort, headaches, or restlessness. It's important to note potential interactions, especially with medications like levodopa used for Parkinson's disease, and to consult with a healthcare provider before starting supplementation.

The applications of Citicoline Sodium are extensive, ranging from enhancing memory and focus in healthy individuals to supporting recovery from neurological conditions. It has been investigated for its role in managing stroke, traumatic brain injury, dementia, and even improving visual function in glaucoma patients. Its neuroprotective effects, stemming from its ability to reinforce the brain's antioxidant systems and stabilize cell membranes, are a cornerstone of its therapeutic value.

For those looking to source Citicoline Sodium, it's available from various manufacturers and suppliers who offer it as a raw material API. When sourcing, key considerations include purity (often exceeding 98%), adherence to pharmacopeial standards like USP or EP, and the availability of supporting documentation such as COAs and MSDS. Reputable suppliers emphasize quality control and offer competitive pricing for bulk quantities.

In summary, Citicoline Sodium is a valuable compound for supporting cognitive health and addressing neurological concerns. Adhering to recommended dosages, being aware of potential mild side effects, and sourcing from trusted manufacturers are crucial steps for maximizing its benefits safely and effectively.