Demeclocycline Hydrochloride (CAS 64-73-3) is a notable member of the tetracycline antibiotic family, primarily known for its effectiveness against a wide array of bacterial infections by inhibiting protein synthesis. However, its therapeutic utility extends to a more specialized area: the treatment of hyponatremia in patients suffering from the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH).

In SIADH, the body produces too much antidiuretic hormone (ADH), leading to excessive water retention and a dilution of sodium in the blood, resulting in hyponatremia. Demeclocycline Hydrochloride intervenes in this process by reducing the kidney's response to ADH. It achieves this by decreasing the expression of aquaporin-2 (AQP2) channels in the renal medulla, thereby lowering water reabsorption. This mechanism helps to restore normal sodium levels in the blood, making it a critical treatment option for this specific condition.

For pharmaceutical professionals, understanding the nuances of pharmaceutical intermediate sourcing for treatments like SIADH is essential. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated Demeclocycline Hydrochloride manufacturer China, ensures the supply of high-quality API. We provide reliable access to this compound, supporting healthcare providers and researchers in their efforts to manage complex conditions.

The market for Demeclocycline Hydrochloride is shaped by its clinical applications, including its use in SIADH. Companies must consider the Demeclocycline Hydrochloride price and availability when planning their inventory and treatment strategies. Our aim is to provide consistent quality and availability, making us a trusted partner for Demeclocycline Hydrochloride API suppliers and end-users alike.

Furthermore, Demeclocycline Hydrochloride serves as an important compound in research, contributing to fields such as pharmaceutical toxicology reference materials. Its unique action on water balance in the kidneys makes it a subject of continued scientific interest.

In summary, Demeclocycline Hydrochloride's role in managing SIADH highlights its specific and valuable pharmacological properties. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this vital pharmaceutical intermediate, supporting advancements in endocrine and electrolyte disorder management.