For procurement managers and R&D scientists in the pharmaceutical sector, securing a consistent supply of high-quality Active Pharmaceutical Ingredients (APIs) is paramount. Irinotecan Hydrochloride, a vital component in advanced cancer therapies, is no exception. If you are looking to buy Irinotecan Hydrochloride API, understanding the landscape of Chinese manufacturers and suppliers is crucial for obtaining the best price and ensuring product integrity.

Irinotecan Hydrochloride, identified by CAS number 100286-90-6, is a semi-synthetic derivative of camptothecin, a natural alkaloid. It functions as a topoisomerase I inhibitor, making it a potent anti-cancer agent used in the treatment of various cancers, most notably colorectal cancer and small-cell lung cancer. Its efficacy and complex chemical structure necessitate a reliable source for this critical pharmaceutical intermediate.

When sourcing from China, it's essential to partner with established manufacturers who adhere to international quality standards, such as GMP. Look for suppliers who can provide detailed Certificates of Analysis (CoA) that confirm the purity and specifications of the Irinotecan Hydrochloride. Key attributes to verify include its appearance (typically a yellow crystalline powder), molecular formula (C33H38N4O6.HCl), and molecular weight (623.14). Understanding these basic properties is the first step in a successful procurement process.

Several factors influence the Irinotecan Hydrochloride price. These include the scale of production, the quality certifications held by the manufacturer, and current market demand. Engaging directly with a reputable Irinotecan Hydrochloride manufacturer in China can often lead to more favorable pricing and direct communication regarding your specific requirements. Many suppliers also offer flexible payment terms and shipping options, including FOB, CFR, and CIF, to accommodate international buyers.

Beyond price, consider the supplier's experience and their ability to provide necessary documentation, such as Drug Master Files (DMF) or regulatory support for your market. A proactive supplier will also have robust logistics capabilities, ensuring timely delivery via air or sea freight to major ports like Shanghai or Qingdao. For those involved in research and development, inquiring about smaller quantities for testing and pilot studies is also a standard practice when you purchase this important API.

In summary, for procurement managers seeking Irinotecan Hydrochloride CAS 100286-90-6, prioritizing quality, reliability, and competitive pricing through vetted Chinese suppliers is key. By conducting thorough due diligence and building strong relationships with manufacturers, you can ensure a stable supply of this vital anti-cancer API.