Osimertinib Mesylate: The Chemistry and Clinical Impact of a Key Lung Cancer Intermediate
NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide insights into Osimertinib Mesylate, a critical chemical entity that has significantly impacted the treatment of lung cancer. Understanding the chemistry and clinical applications of this pharmaceutical intermediate is key for professionals in the pharmaceutical sector.
Osimertinib Mesylate is chemically known as the mesylate salt of osimertinib. Its molecular formula is C29H37N7O5S, with a molecular weight of 595.7 g/mol. This compound functions as a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. Its mechanism of action involves selectively and irreversibly binding to mutant EGFR proteins, particularly those with common mutations found in non-small cell lung cancer (NSCLC), such as T790M, L858R, and exon 19 deletions. This precise targeting is crucial for its therapeutic effectiveness.
Clinically, Osimertinib Mesylate has shown remarkable efficacy in treating patients with advanced or metastatic NSCLC who possess specific EGFR mutations. It is also used as an adjuvant treatment in certain post-operative NSCLC cases. The drug's ability to overcome resistance mechanisms developed against earlier EGFR inhibitors makes it an indispensable component in modern cancer care strategies. For pharmaceutical companies, the availability of Osimertinib Mesylate API in a pure powder form is essential for developing and manufacturing these advanced therapies.
When sourcing Osimertinib Mesylate powder, it is vital to consider factors such as purity, batch consistency, and compliance with international pharmaceutical standards. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to meeting these requirements, ensuring that our clients receive reliable pharmaceutical intermediates. Whether you are involved in drug discovery, process development, or large-scale manufacturing, understanding the market for Osimertinib Mesylate CAS 1421373-66-1 and its associated pricing is crucial for efficient project management.
The continuous research and development in targeted therapies highlight the growing importance of compounds like Osimertinib Mesylate. By providing high-quality APIs and intermediates, NINGBO INNO PHARMCHEM CO.,LTD. plays a supportive role in advancing medical treatments and improving patient outcomes in the fight against lung cancer. We are committed to being your trusted partner in sourcing essential pharmaceutical materials.
Perspectives & Insights
Logic Thinker AI
“Clinically, Osimertinib Mesylate has shown remarkable efficacy in treating patients with advanced or metastatic NSCLC who possess specific EGFR mutations.”
Molecule Spark 2025
“The drug's ability to overcome resistance mechanisms developed against earlier EGFR inhibitors makes it an indispensable component in modern cancer care strategies.”
Alpha Pioneer 01
“For pharmaceutical companies, the availability of Osimertinib Mesylate API in a pure powder form is essential for developing and manufacturing these advanced therapies.”