For pharmaceutical companies specializing in veterinary medicine, securing a consistent and high-quality supply of Active Pharmaceutical Ingredients (APIs) is paramount. Enrofloxacin Hydrochloride (CAS 112732-17-9) stands out as a critical synthetic antibacterial agent, widely utilized for its efficacy against a broad spectrum of bacterial pathogens affecting livestock, poultry, aquaculture, and companion animals. This article serves as a guide for procurement managers and R&D scientists looking to source this vital API from reputable manufacturers and suppliers, particularly those based in China.

Understanding Enrofloxacin Hydrochloride's Value Proposition
Enrofloxacin Hydrochloride, a fluoroquinolone, is renowned for its broad-spectrum activity, effectively targeting both Gram-negative and Gram-positive bacteria. Its mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and repair. This makes it a cornerstone in treating conditions such as respiratory infections, gastrointestinal infections, skin and wound infections, and septicemia in animals. The high oral bioavailability and excellent tissue penetration of Enrofloxacin Hydrochloride further enhance its utility, ensuring therapeutic concentrations are reached where they are most needed.

Key Considerations When Sourcing Enrofloxacin Hydrochloride
When engaging with potential suppliers for Enrofloxacin Hydrochloride, several factors are critical to ensure a successful procurement. Firstly, quality is non-negotiable. Buyers should seek manufacturers that can provide detailed Certificates of Analysis (CoA) confirming purity, assay (typically >98.5% for the hydrochloride salt), and low levels of impurities like fluoroquinolonic acid. Verify that the product meets relevant pharmacopoeia standards such as USP, EP, or BP if applicable to your target markets.

Secondly, supply chain reliability is crucial. For large-scale manufacturing, consistent availability and production capacity (e.g., 10MT/month or more) are vital. Buyers should inquire about the supplier's production capabilities, lead times, and their ability to handle fluctuating demand. A stable manufacturer with a strong track record ensures uninterrupted production of your veterinary drugs. Many suppliers from China, like NINGBO INNO PHARMCHEM CO.,LTD., emphasize their robust supply chain and manufacturing expertise.

Thirdly, competitive pricing is a significant driver in the pharmaceutical industry. While quality and reliability are paramount, cost-effectiveness directly impacts product margins. Engaging with manufacturers directly, especially those in China known for their production efficiencies, can yield significant cost savings. It's advisable to obtain quotes from multiple suppliers to benchmark prices for bulk purchases of Enrofloxacin Hydrochloride.

Navigating the Chinese API Market for Enrofloxacin Hydrochloride
China has emerged as a global hub for API manufacturing, offering a vast array of products, including Enrofloxacin Hydrochloride. Pharmaceutical companies can find numerous manufacturers and trading companies offering this API. When choosing a supplier, look for established companies with certifications like ISO or GMP, indicating adherence to quality manufacturing practices. Companies that offer custom synthesis or specialized packaging options can also provide added value. For instance, understanding the typical specifications like appearance (white to off-white crystalline powder), solubility, and stability is important when evaluating a manufacturer's product data.

Making the Purchase Decision
To buy Enrofloxacin Hydrochloride effectively, prospective buyers should clearly define their requirements regarding quantity, purity, and delivery timelines. Direct inquiries to manufacturers and suppliers are recommended to obtain the latest pricing and product specifications. Platforms like echemi.com or chemicalbook.com list numerous suppliers, facilitating the initial vendor identification process. However, thorough due diligence on the supplier’s credentials, production facilities, and quality control processes is essential. Consider partnering with a supplier that offers ongoing technical support and responsive customer service. For those seeking a reliable source, exploring options from experienced Chinese manufacturers is a strategic move to secure high-quality Enrofloxacin Hydrochloride at competitive prices.