For pharmaceutical formulators and product development scientists, understanding the precise chemical properties and stability of an API like Tamoxifen (CAS 10540-29-1) is fundamental to successful formulation and manufacturing. This detailed look into Tamoxifen’s physical and chemical characteristics, combined with sourcing insights, is crucial for B2B professionals.

Tamoxifen, with its molecular formula C26H29NO, presents as a white crystalline solid. Key physical properties include a melting point typically ranging from 97-98°C (literature values). Its solubility characteristics are also important for formulation design: it is generally insoluble in water but soluble in organic solvents such as DMF, methanol, and DMSO. Understanding these solubility parameters is vital for developing stable and bioavailable drug products.

Stability is a critical factor for any API. Tamoxifen generally requires storage at specific temperatures, often recommended at 2-8°C or -20°C, depending on its form and supplier recommendations, to maintain its integrity and prevent degradation. Manufacturers meticulously control the synthesis and purification processes to ensure the highest isomer purity (specifically the Z isomer for therapeutic activity) and minimize impurities. This attention to detail is reflected in the product's CoA, which details parameters like assay purity, related substances, and residual solvents.

When considering formulation, formulators must also account for Tamoxifen's known metabolic pathways. As a prodrug, it is converted into active metabolites, 4-hydroxytamoxifen and endoxifen, primarily by hepatic CYP enzymes. While this is primarily a biological process, understanding the compound’s inherent stability under various conditions relevant to drug processing (e.g., heat, pH changes during manufacturing) is essential. Suppliers provide this data to aid in successful product development.

For those looking to buy Tamoxifen, sourcing from a reliable manufacturer who provides comprehensive technical data is paramount. We, as a dedicated supplier, offer Tamoxifen with guaranteed purity and detailed stability profiles. Our commitment extends to providing all necessary documentation, including MSDS and CoA, to facilitate your formulation work and ensure regulatory compliance. Accessing competitive Tamoxifen prices from dependable suppliers in China allows for cost-effective development cycles.

The ability to reliably purchase Tamoxifen with consistent physical and chemical properties directly impacts the success of pharmaceutical development. Whether it’s for investigational new drugs or established therapies, ensuring the quality and stability of the API is a non-negotiable aspect of the process. We are committed to being a trusted partner for formulators, providing the essential building blocks for innovative pharmaceutical solutions.