For professionals in the pharmaceutical sector, securing reliable sources for Active Pharmaceutical Ingredients (APIs) like Tamoxifen (CAS 10540-29-1) is paramount. Understanding the compound's properties, applications, and the nuances of sourcing is key to successful research and development.

Tamoxifen, a synthetic non-steroidal anti-estrogen, plays a pivotal role in various therapeutic research areas. Its primary mechanism involves acting as a selective estrogen response modifier (SERM). This means it can exhibit both estrogenic and anti-estrogenic effects, depending on the tissue and the specific biological context. This characteristic makes it invaluable in studies focusing on hormone-dependent diseases, particularly breast cancer, where it competes with estrogen for binding to estrogen receptors (ERs).

Beyond its endocrine effects, Tamoxifen is also recognized as a protein kinase C (PKC) inhibitor. PKC is a family of enzymes that play critical roles in cell signaling pathways that regulate cell growth, differentiation, and survival. By inhibiting PKC, Tamoxifen can influence these cellular processes, making it a subject of interest in oncology and other research fields investigating cellular regulation.

The anti-angiogenic properties of Tamoxifen further enhance its therapeutic potential. Angiogenesis, the formation of new blood vessels, is crucial for tumor growth and metastasis. Tamoxifen's ability to inhibit this process is a significant area of study in developing anti-cancer strategies.

Key Applications and Research Focus:

  • Breast Cancer Research: Tamoxifen is a cornerstone in the study and treatment of estrogen-receptor-positive breast cancer, aiming to reduce recurrence and improve survival rates.
  • Fertility Studies: Historically, Tamoxifen has been used to stimulate ovulation in anovulatory infertility patients, making it relevant for reproductive health research.
  • Cellular Signaling: Its role as a PKC inhibitor makes it a valuable tool for dissecting complex cell signaling cascades and understanding their implications in various diseases.

Sourcing Tamoxifen: A Manufacturer's Perspective

When looking to buy Tamoxifen, it is essential to partner with a reputable manufacturer and supplier. For businesses seeking Tamoxifen in China, understanding the quality standards and logistical capabilities is crucial. We, as a dedicated supplier, offer Tamoxifen with a guaranteed purity of ≥99% (HPLC), supported by comprehensive technical documentation like MSDS and TDS. This ensures that researchers and formulators receive a product that meets stringent industry requirements.

Procuring chemical intermediates and APIs requires a focus on cost-effectiveness without compromising quality. By sourcing directly from manufacturers, businesses can obtain competitive Tamoxifen prices and ensure a stable supply chain. Enquiries for quotes are welcome to discuss bulk purchasing and specific product needs. We understand the importance of timely delivery and reliable product consistency for your research projects.

For those interested in the Tamoxifen synthesis process, our commitment to transparency means providing information that aids in understanding the compound's origin and manufacturing rigor. Whether your research is focused on novel cancer therapies, cellular mechanisms, or other pharmaceutical applications, Tamoxifen (CAS 10540-29-1) remains a vital compound. As a trusted Tamoxifen supplier, we are here to support your scientific endeavors.