Tegafur, with the CAS number 17902-23-7, is a fascinating molecule from a chemical perspective, crucial for its role in advanced cancer treatments. Its chemical name is 1-(tetrahydro-2-furyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione, and its molecular formula is C8H9FN2O3, with a molecular weight of approximately 200.17 g/mol. This structure is key to its function as a prodrug, which is activated within the body to release the potent antineoplastic agent, 5-fluorouracil (5-FU).

The physical properties of Tegafur API, typically described as a white to off-white crystalline powder, are important for its handling and formulation in pharmaceutical manufacturing. Its solubility characteristics – soluble in methanol and chloroform, slightly soluble in water and ethanol, and almost insoluble in benzene and ether – dictate the solvents and processes used in drug development. Understanding these properties is vital for optimizing drug delivery systems and ensuring the stability and bioavailability of the final medicinal product.

NINGBO INNO PHARMCHEM CO.,LTD. specializes in the meticulous manufacturing of Tegafur API, adhering to stringent production protocols. Our process involves precise chemical synthesis to ensure the highest purity and consistency, meeting critical pharmacopoeial standards such as CP and JP. The manufacturing process is carefully controlled to manage aspects like particle size and crystalline form, which can influence the API's performance in final drug formulations. Our expertise ensures that the Tegafur API we supply is of pharmaceutical grade.

The manufacturing of APIs like Tegafur requires specialized knowledge and adherence to Good Manufacturing Practices (GMP). NINGBO INNO PHARMCHEM CO.,LTD. is committed to these standards, ensuring that every batch of Tegafur API is produced under controlled conditions. This dedication to manufacturing excellence not only guarantees the quality of our product but also supports the pharmaceutical companies that rely on us for their critical drug development needs, particularly in the challenging field of oncology.