At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing high-quality pharmaceutical intermediates that support the development of groundbreaking treatments. Tofacitinib Citrate Powder Intermediate is one such vital chemical, playing a crucial role in the management of Psoriasis, a chronic skin condition characterized by inflammation and rapid skin cell turnover.

Psoriasis affects millions worldwide, causing itchy, scaly patches on the skin. It is an autoimmune condition where the body's immune system mistakenly attacks healthy skin cells, triggering an inflammatory response. Effective treatment often involves modulating this overactive immune system to reduce inflammation and slow down the rapid growth of skin cells.

Tofacitinib Citrate, a sophisticated oral small molecule JAK inhibitor, offers a targeted approach to managing Psoriasis. By inhibiting specific Janus kinase (JAK) pathways, particularly JAK1 and JAK3, it effectively interrupts the signaling cascades that drive inflammation in Psoriasis. This mechanism helps to calm the overactive immune system, reducing the redness, scaling, and inflammation characteristic of the condition. The compound's efficacy as an API for psoriasis treatment is well-documented.

The high purity of Tofacitinib Citrate Powder Intermediate, exceeding 99%, is essential for creating safe and effective pharmaceutical products. This ensures that the final medication delivers consistent therapeutic benefits. Furthermore, its favorable Tofacitinib citrate solubility and oral bioavailability of 74% make it an ideal candidate for oral formulations, offering patients a convenient alternative to injectable treatments.

The application of Tofacitinib Citrate extends beyond Psoriasis, demonstrating its broad utility in treating various immune-mediated inflammatory diseases, including Rheumatoid Arthritis and Ulcerative Colitis. Its ability to regulate immune responses makes it a valuable tool in the pharmacopoeia for managing chronic inflammatory conditions.

NINGBO INNO PHARMCHEM CO.,LTD. takes pride in supplying this critical API for psoriasis treatment, contributing to the development of advanced therapies that improve the lives of patients. By providing high-quality Tofacitinib Citrate Powder Intermediate, we enable pharmaceutical companies to bring innovative solutions to market, offering new hope for those affected by Psoriasis and other debilitating inflammatory diseases.