The fight against breast cancer has been significantly advanced by targeted therapies, among which aromatase inhibitors (AIs) hold a prominent position. Letrozole, a leading AI, represents a critical tool in modern oncology. Understanding its mechanism of action reveals why it is indispensable in hormone-sensitive breast cancer treatment.

Letrozole (CAS 112809-51-5) belongs to the third-generation class of non-steroidal aromatase inhibitors. Its primary function is to block the aromatase enzyme, which is responsible for the conversion of androgens (like testosterone and androstenedione) into estrogens. In post-menopausal women, this enzymatic process is the main pathway for estrogen production. By inhibiting aromatase, Letrozole effectively lowers circulating estrogen levels to post-menopausal baseline levels. This reduction in estrogen is crucial because many breast cancers, particularly those classified as hormone receptor-positive (ER-positive and/or PR-positive), rely on estrogen to fuel their growth and proliferation.

The clinical application of Letrozole is extensive. It is commonly used as adjuvant therapy after surgery to reduce the risk of recurrence in early-stage breast cancer. For patients with advanced or metastatic breast cancer, Letrozole can help slow tumor growth, alleviate symptoms, and improve overall survival. NINGBO INNO PHARMCHEM CO.,LTD. supplies Letrozole with a guaranteed purity of 99%min, ensuring that the drug's potent inhibitory action is delivered effectively. Our commitment to quality makes us a reliable source for this vital pharmaceutical intermediate.

The efficacy of Letrozole underscores the importance of high-quality pharmaceutical ingredients. When healthcare professionals choose to buy Letrozole from NINGBO INNO PHARMCHEM CO.,LTD., they are opting for a product that adheres to strict quality standards, including USP, BP, EP, and FCC. This dedication to excellence ensures that the therapeutic potential of Letrozole is fully realized in patient care, reinforcing its status as a key player in breast cancer management and hormone therapy.