Cefazolin Sodium Salt, identified by CAS number 27164-46-1, is a critical pharmaceutical ingredient with a defined set of chemical properties and specifications that are essential for its effective use in medicine and research. As a first-generation cephalosporin antibiotic, its molecular structure and purity directly influence its therapeutic efficacy and reliability in analytical applications.

Chemically, Cefazolin Sodium Salt has the molecular formula C14H13N8NaO4S3 and a molecular weight of approximately 476.49 g/mol. Its physical appearance is typically described as a white or gray crystalline powder, often with a slight odor and a bitter taste. These characteristics are important for identification and quality assessment. Key specifications often include purity, typically measured by HPLC, with a requirement of 95.0-102.0% or higher for pharmaceutical-grade products. Other critical parameters include pH levels (usually 4.5-6) and water content (maximum 6%), which affect its stability and solubility.

The solubility of Cefazolin Sodium Salt is good in water, making it suitable for intravenous and intramuscular administration. However, its solubility in organic solvents like acetone or chloroform is limited, which is a consideration in its formulation and handling. Storage conditions are also vital; it should be kept away from light and stored airtight, often under refrigerated conditions (-18°C to 4°C) depending on the specific product and packaging, to maintain its potency and prevent degradation.

For pharmaceutical manufacturers and researchers, sourcing Cefazolin Sodium Salt that meets these precise specifications is paramount. Partnering with reputable Cefazolin Sodium Salt suppliers and manufacturers who adhere to strict quality control measures ensures that the purchased material is fit for its intended purpose. Whether for bulk production of antibiotics or for delicate analytical research, understanding and verifying these specifications is a fundamental aspect of the procurement process. When you buy Cefazolin Sodium Salt, always consult the supplier's specifications and CoA to confirm it meets your project's requirements.