Cidofovir (CAS NO: 113852-37-2) is a potent synthetic antiviral agent that has proven crucial in managing serious viral infections, particularly Cytomegalovirus (CMV) retinitis in immunocompromised individuals. As a nucleoside analogue, its therapeutic efficacy stems from its unique mechanism of action. Once inside the host cell, Cidofovir is phosphorylated by cellular enzymes to its active diphosphate metabolite. This active form closely resembles natural nucleotides and competitively inhibits viral DNA polymerase. By integrating into the growing viral DNA chain, it effectively halts further DNA polymerization, thus disrupting the replication cycle of viruses like CMV. This makes it an invaluable option for patients with conditions like AIDS, where their immune systems are compromised, leaving them vulnerable to opportunistic infections.

The primary indication for Cidofovir is the treatment of CMV retinitis, an inflammation of the retina caused by the cytomegalovirus that can lead to blindness. It is administered intravenously under medical supervision. Beyond its established use, research and clinical observations have explored Cidofovir's potential in other areas, notably in dermatology. Topical applications of Cidofovir have shown promise in treating viral skin conditions such as warts, including anogenital warts, and molluscum contagiosum. These off-label uses highlight the compound's broad antiviral spectrum. However, it's essential to understand the Cidofovir side effects and precautions associated with its use. Potential adverse effects can include kidney toxicity, neutropenia (low white blood cell count), and ocular issues. Therefore, careful monitoring by healthcare professionals is paramount. When considering Cidofovir, understanding its price and availability from reliable manufacturers and suppliers is also a key factor for healthcare providers and institutions. For those seeking this critical pharmaceutical, sourcing high-quality Cidofovir with consistent purity is vital for effective treatment outcomes. Exploring options to buy Cidofovir often leads to specialized chemical suppliers who can provide detailed product specifications and support.