Understanding CYP17 Inhibitors: The Role of Abiraterone Acetate
The scientific understanding of how to combat complex diseases like castration-resistant prostate cancer (CRPC) has advanced significantly. A key area of focus has been on targeting the hormonal pathways that drive cancer growth. This is where CYP17 inhibitors, such as Abiraterone Acetate, play a crucial role. As a leading manufacturer and supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to this field by offering high-purity Abiraterone Acetate (CAS 154229-18-2).
CYP17, also known as 17α-hydroxylase/C17,20-lyase, is an enzyme essential for the synthesis of androgens. In many prostate cancers, even after androgen deprivation therapy, the cancer cells can adapt and find alternative sources of androgens or develop ways to become less reliant on them. However, by inhibiting CYP17, abiraterone acetate effectively blocks the production of androgens in the testes, adrenal glands, and crucially, within the prostate tumor itself.
The pharmaceutical intermediate, Abiraterone Acetate, is the acetyl ester prodrug of abiraterone. This means that once administered, it is metabolized into its active form, abiraterone. This targeted action makes it a powerful tool in the fight against CRPC. Understanding the mechanism of CYP17 inhibitors is vital for appreciating the value of sourcing quality raw materials. For researchers and pharmaceutical companies looking to buy Abiraterone Acetate, partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to a product that meets stringent quality standards.
Our commitment as a supplier in China extends beyond just providing the chemical compound. We aim to be a partner in the advancement of medical treatments. The high purity of our Abiraterone Acetate (99%) is a testament to our dedication to quality, ensuring that the final pharmaceutical products are safe and effective for patients battling advanced prostate cancer. This focus on providing essential pharmaceutical intermediates like Abiraterone Acetate is central to our mission.
CYP17, also known as 17α-hydroxylase/C17,20-lyase, is an enzyme essential for the synthesis of androgens. In many prostate cancers, even after androgen deprivation therapy, the cancer cells can adapt and find alternative sources of androgens or develop ways to become less reliant on them. However, by inhibiting CYP17, abiraterone acetate effectively blocks the production of androgens in the testes, adrenal glands, and crucially, within the prostate tumor itself.
The pharmaceutical intermediate, Abiraterone Acetate, is the acetyl ester prodrug of abiraterone. This means that once administered, it is metabolized into its active form, abiraterone. This targeted action makes it a powerful tool in the fight against CRPC. Understanding the mechanism of CYP17 inhibitors is vital for appreciating the value of sourcing quality raw materials. For researchers and pharmaceutical companies looking to buy Abiraterone Acetate, partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to a product that meets stringent quality standards.
Our commitment as a supplier in China extends beyond just providing the chemical compound. We aim to be a partner in the advancement of medical treatments. The high purity of our Abiraterone Acetate (99%) is a testament to our dedication to quality, ensuring that the final pharmaceutical products are safe and effective for patients battling advanced prostate cancer. This focus on providing essential pharmaceutical intermediates like Abiraterone Acetate is central to our mission.
Perspectives & Insights
Data Seeker X
“In many prostate cancers, even after androgen deprivation therapy, the cancer cells can adapt and find alternative sources of androgens or develop ways to become less reliant on them.”
Chem Reader AI
“However, by inhibiting CYP17, abiraterone acetate effectively blocks the production of androgens in the testes, adrenal glands, and crucially, within the prostate tumor itself.”
Agile Vision 2025
“The pharmaceutical intermediate, Abiraterone Acetate, is the acetyl ester prodrug of abiraterone.”