Diazoxide, a compound with the CAS number 364-98-7, plays a pivotal role in the pharmaceutical industry as a key active pharmaceutical ingredient (API). Its chemical structure and properties are fundamental to its therapeutic efficacy, making it a subject of significant interest for researchers and manufacturers alike. Understanding the detailed chemical and physical characteristics of Diazoxide is the first step in appreciating its clinical value and manufacturing requirements.

The compound presents as a white powder, a common form for many APIs, which typically indicates a high degree of purity. Its molecular formula, C8H7ClN2O2S, and a molecular weight of 230.67 g/mol are critical identifiers. The MeSH classification identifies it as an Antihypertensive Agent and a Vasodilator Agent, underscoring its primary cardiovascular action. The pharmacological mechanism of Diazoxide involves its action as a potassium channel activator. By enhancing the permeability of cell membranes to potassium ions, it causes the relaxation of arteriolar smooth muscles. This action leads to a decrease in peripheral vascular resistance, consequently lowering blood pressure. This distinct mechanism differentiates it from thiazide diuretics, despite their structural similarity, as it lacks significant diuretic activity.

Clinically, Diazoxide is utilized in two main therapeutic areas. It is administered parentally to manage hypertensive emergencies, a critical condition requiring immediate medical intervention. Furthermore, it is employed to treat hypoglycemia, particularly when it is secondary to insulinoma. By inhibiting insulin release from the pancreas, Diazoxide helps to regulate blood glucose levels. This dual action makes it an indispensable drug in critical care and endocrinology. The extensive list of synonyms, including Proglycem and Hyperstat, further attests to its widespread recognition and use in medical practice.

For companies looking to source this vital pharmaceutical intermediate, a robust supply chain is essential. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality Diazoxide, ensuring that manufacturers have access to a reliable supply. The ability to purchase Diazoxide API from reputable sources with proper documentation is critical for regulatory compliance and product safety. As the pharmaceutical industry continues to advance, the demand for effective compounds like Diazoxide remains strong, driving continuous research and development in its applications and production.

The market for pharmaceutical raw materials like Diazoxide is competitive, emphasizing the need for efficient sourcing and stringent quality control. We recognize the importance of providing comprehensive information to our clients, enabling informed decisions regarding their procurement needs. By focusing on the chemical properties, pharmacological actions, and therapeutic applications of Diazoxide, we aim to support the pharmaceutical community in its mission to provide effective healthcare solutions.