Understanding Nystatin CAS 1400-61-9: Applications in Pharmaceutical Formulations
Nystatin, identified by CAS number 1400-61-9, is a vital antifungal agent widely recognized for its efficacy against a spectrum of fungal infections, particularly those caused by Candida species. As a pharmaceutical ingredient manufacturer, understanding the comprehensive applications of Nystatin is crucial for developing effective and targeted therapeutic solutions.
The primary application of Nystatin is in the treatment of candidiasis, commonly known as yeast infections. This includes:
- Oral Candidiasis (Thrush): Nystatin is a cornerstone in treating oral thrush, a prevalent infection affecting the mouth and throat, especially in infants, immunocompromised individuals, and those using broad-spectrum antibiotics. Pharmaceutical companies utilize Nystatin in oral suspensions and troches to deliver the antifungal agent directly to the affected mucosal surfaces.
- Gastrointestinal Candidiasis: Infections of the stomach and intestines caused by Candida can also be effectively managed with Nystatin. Formulations designed for oral administration ensure that the API reaches the gastrointestinal tract to combat fungal overgrowth.
- Topical Cutaneous Candidiasis: Nystatin is also formulated into creams, ointments, and powders for treating skin infections. These formulations are particularly useful for candidiasis occurring in skin folds, diaper areas, and other moist environments where fungal growth is common.
The effectiveness of Nystatin is attributed to its mechanism of action, where it binds to ergosterol in the fungal cell membrane, leading to increased permeability and cell death. Its limited systemic absorption when used topically or orally contributes to a favorable safety profile, making it a preferred choice for many treatment regimens.
For pharmaceutical manufacturers, sourcing Nystatin with high purity, such as our 99% minimum assay product that meets USP, BP, EP, and FCC standards, is essential. This ensures the potency and safety of the final drug product. When you buy Nystatin from a reputable manufacturer and supplier in China, you gain access to a consistent supply of a crucial ingredient that meets global pharmaceutical requirements.
Whether you are developing a new antifungal medication or seeking a reliable source for an existing product, our Nystatin CAS 1400-61-9 offers the quality and consistency required. We are dedicated to providing pharmaceutical-grade ingredients that empower healthcare innovation. Contact us to discuss your formulation needs and to secure your supply of this indispensable antifungal API.
Perspectives & Insights
Chem Catalyst Pro
“These formulations are particularly useful for candidiasis occurring in skin folds, diaper areas, and other moist environments where fungal growth is common.”
Agile Thinker 7
“The effectiveness of Nystatin is attributed to its mechanism of action, where it binds to ergosterol in the fungal cell membrane, leading to increased permeability and cell death.”
Logic Spark 24
“Its limited systemic absorption when used topically or orally contributes to a favorable safety profile, making it a preferred choice for many treatment regimens.”