Understanding Phentolamine Mesilate CAS 65-28-1: A Key Vasodilator for Medical Applications
The chemical compound Phentolamine Mesilate, identified by its CAS number 65-28-1, is a significant player in the pharmaceutical industry, primarily recognized for its potent vasodilatory properties. NINGBO INNO PHARMCHEM CO.,LTD. provides this high-purity compound, which serves as a critical raw material for a range of medical treatments. Understanding the specific attributes and applications of this alpha-blocker is crucial for researchers and pharmaceutical manufacturers alike.
As a non-selective alpha-adrenergic receptor antagonist, Phentolamine Mesilate exerts its primary effect by blocking alpha-adrenergic receptors. This action counteracts the effects of vasoconstrictors like norepinephrine and epinephrine, leading to relaxation of smooth muscles in blood vessels. This relaxation causes vasodilation, increasing blood flow and reducing peripheral resistance. This mechanism is fundamental to its therapeutic use in conditions where improved blood circulation is necessary.
A major area where this vasodilator raw material finds application is in the treatment of erectile dysfunction. By promoting increased blood flow to the penile tissues, Phentolamine Mesilate aids in achieving and maintaining an erection. Pharmaceutical companies often rely on suppliers like NINGBO INNO PHARMCHEM CO.,LTD. to source pharmaceutical grade phentolamine mesilate powder, ensuring the efficacy and safety of their final products. The search for quality phentolamine mesilate for sale is a common undertaking for formulators in this sector.
Furthermore, Phentolamine Mesilate plays a vital role in more critical medical situations. It is used in the management of hypertensive crises that can arise during surgery for pheochromocytoma, helping to control dangerously high blood pressure. Its ability to counteract severe vasoconstriction also makes it valuable in reversing tissue necrosis caused by the accidental leakage of potent vasoconstrictive drugs, such as norepinephrine, into surrounding tissues during intravenous administration.
The availability of Phentolamine Mesilate CAS 65-28-1 as a reliable raw material is essential for continuous research and development in pharmacological sciences. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its product meets the high standards required for pharmaceutical manufacturing, offering a consistent and dependable supply. The company’s commitment to quality means that clients can purchase phentolamine mesilate powder with confidence, knowing they are obtaining a material suitable for demanding applications.
In summary, Phentolamine Mesilate Powder (CAS 65-28-1) is a critical pharmaceutical ingredient known for its vasodilatory and alpha-blocking capabilities. Its applications span from treating erectile dysfunction to managing severe medical emergencies. For pharmaceutical companies and researchers seeking this essential compound, NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier supplier, providing the high purity and quality necessary for advanced medical solutions.
Perspectives & Insights
Logic Thinker AI
“As a non-selective alpha-adrenergic receptor antagonist, Phentolamine Mesilate exerts its primary effect by blocking alpha-adrenergic receptors.”
Molecule Spark 2025
“This action counteracts the effects of vasoconstrictors like norepinephrine and epinephrine, leading to relaxation of smooth muscles in blood vessels.”
Alpha Pioneer 01
“This relaxation causes vasodilation, increasing blood flow and reducing peripheral resistance.”