While Tolfenamic acid is widely recognized for its efficacy as a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties, recent scientific investigations are uncovering its potential in a more complex therapeutic area: oncology. The exploration of Tolfenamic acid anti-neoplastic activity is opening new frontiers in cancer treatment research.

The underlying Tolfenamic acid mechanism of action as an NSAID involves inhibiting cyclooxygenase (COX) enzymes. However, its anti-cancer effects appear to extend beyond this primary mechanism. Research indicates that Tolfenamic acid can exert anti-tumor effects through pathways that are both COX-dependent and COX-independent. These mechanisms include inducing the production of reactive oxygen species (ROS), causing DNA damage in cancer cells, and modulating key signaling pathways such as NF-kB activation.

Specifically, Tolfenamic acid has been observed to increase the expression of activating transcription factor 3 (ATF3) and NSAID-activated gene-1 (NAG1), while simultaneously inhibiting specificity proteins (Sp). This intricate molecular interplay leads to reduced expression of Sp-dependent proteins that promote cell survival and growth, thereby enhancing tumor cell apoptosis and inhibiting tumor growth and angiogenesis. These findings are significant for anyone interested in Tolfenamic acid pharmaceutical applications beyond traditional pain and inflammation management.

For researchers and pharmaceutical companies investigating these novel applications, sourcing high-purity Tolfenamic acid is crucial. When looking for Tolfenamic acid CAS 13710-19-5 suppliers, it is important to ensure the material is suitable for advanced research and development. NINGBO INNO PHARMCHEM CO.,LTD. provides Tolfenamic acid that meets high purity standards, supporting critical research efforts in understanding and potentially utilizing its anti-neoplastic properties. This commitment to quality ensures that researchers can rely on the material for accurate and reproducible experimental results.

The dual nature of Tolfenamic acid – its established role as an NSAID and its emerging potential in cancer therapy – makes it a compound of significant interest. As research progresses, the importance of understanding its Tolfenamic acid chemical properties and ensuring a reliable supply chain becomes even more pronounced. For those looking to buy Tolfenamic Acid for research or pharmaceutical development, NINGBO INNO PHARMCHEM CO.,LTD. offers a trusted source for this versatile compound.