L-Histidine, identified by CAS number 71-00-1, is more than just an essential amino acid; it's a molecule with a distinctive chemical profile that makes it exceptionally valuable in pharmaceutical innovation. As a leading L-Histidine manufacturer and supplier, we focus on delivering a product whose inherent chemical properties meet the rigorous demands of the pharmaceutical industry.

The defining feature of L-Histidine is its imidazole side chain. This heterocyclic aromatic ring contains two nitrogen atoms, one of which can readily accept or donate a proton. This amphoteric nature, particularly the pKa of its side chain (around 6.0), allows L-Histidine to function effectively as a buffer in a pH range crucial for many biological and pharmaceutical processes, especially around neutral pH. This buffering capacity is critical for maintaining the stability of sensitive molecules, including proteins and peptides, used in drug formulations.

Beyond buffering, the imidazole ring's ability to coordinate with metal ions is another significant chemical property. L-Histidine can act as a bidentate ligand, chelating metal ions like copper, iron, and zinc. This metal-binding capability is leveraged in several ways in pharmaceuticals: it can stabilize protein structures by interacting with metalloproteins, and it can help prevent metal-catalyzed degradation reactions that might compromise drug integrity. This makes L-Histidine a valuable component for pharmaceutical excipients and active pharmaceutical ingredients (APIs).

For companies looking to buy L-Histidine, understanding these chemical attributes is key to selecting the right grade and supplier. Our manufacturing process is optimized to ensure the highest purity and consistent chemical properties of L-Histidine, suitable for demanding pharmaceutical applications. We serve as a reliable source for this versatile amino acid, offering competitive L-Histidine prices for bulk requirements. As your trusted L-Histidine manufacturer in China, we are dedicated to supporting your R&D and production needs with top-tier chemical raw materials.

We encourage you to reach out for detailed technical specifications and to discuss how our L-Histidine can benefit your pharmaceutical formulations. Partner with us for chemical excellence and reliable supply.