Swine dysentery, also known as bloody scours, is a significant economic threat to pig farming worldwide. Caused by the bacterium Brachyspira hyodysenteriae, this disease leads to severe intestinal inflammation, diarrhea, reduced growth rates, and increased mortality if not managed effectively. Among the arsenal of treatments available, Tylosin Tartrate stands out as a particularly effective agent, especially when used in conjunction with proper management practices. This article delves into the efficacy of Tylosin Tartrate for swine, focusing on its application in controlling swine dysentery and porcine proliferative enteropathies (PPE).

Tylosin Tartrate is a macrolide antibiotic that works by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit. This action effectively halts the growth and reproduction of susceptible bacteria. In swine, it is highly effective against Brachyspira hyodysenteriae and Lawsonia intracellularis, the causative agent of PPE. The water-soluble nature of Tylosin Tartrate makes it an ideal choice for administration via drinking water, a common and efficient method for treating entire herds. When used to control swine dysentery, the recommended dosage is typically 250 mg per gallon of drinking water for 3 to 10 days, depending on the severity of the infection. Following this initial treatment, a follow-up with a medicated feed containing Tylosin Type A articles for 2 to 6 weeks can help maintain gut health and prevent recurrence.

Similarly, for the control of porcine proliferative enteropathies (PPE), which leads to thickening of the intestinal lining and reduced nutrient absorption, Tylosin Tartrate administered in drinking water (250 mg/gallon for 3-10 days) followed by medicated feed (40-100 g/ton for 2-6 weeks) has proven effective. These treatment protocols, guided by veterinary advice, are crucial for preventing significant economic losses in swine operations. However, it is important to adhere to withdrawal periods before slaughter to ensure product safety. Always consult with a veterinarian to determine the most appropriate treatment plan and dosage for your specific herd. Choosing the right antibiotic like Tylosin Tartrate for swine is key to maintaining healthy and productive livestock.