Tylvalosin Tartrate: Mechanism and Applications in Swine Health
The health of swine herds is critically dependent on effective disease management, with antibiotics playing a pivotal role in preventing and treating bacterial infections. Tylvalosin Tartrate, a semi-synthetic macrolide antibiotic, has emerged as a vital tool for veterinarians and farmers dealing with prevalent issues like Porcine Proliferative Enteropathy (PPE) and Swine Respiratory Disease (SRD). Understanding its mechanism of action and specific applications is key for optimal utilization.
Tylvalosin Tartrate functions by inhibiting bacterial protein synthesis. It achieves this by binding to the 50S ribosomal subunit of susceptible bacteria, specifically targeting the 23S rRNA. This action disrupts the translation process, halting bacterial growth and reproduction. Its efficacy extends to a broad spectrum of pathogens commonly implicated in swine diseases, including Lawsonia intracellularis (the causative agent of PPE), Mycoplasma hyopneumoniae, Pasteurella multocida, and Brachyspira spp.
The primary applications of Tylvalosin Tartrate in swine health are focused on combating two major health challenges:
- Porcine Proliferative Enteropathy (PPE): This intestinal disease, caused by Lawsonia intracellularis, leads to significant economic losses through reduced growth rates and poor feed conversion. Tylvalosin Tartrate is highly effective in controlling this infection, administered typically via feed or drinking water.
- Swine Respiratory Disease (SRD): A complex of diseases affecting the respiratory tract, SRD can be caused by various bacterial agents. Tylvalosin Tartrate's activity against key respiratory pathogens like Mycoplasma hyopneumoniae and Pasteurella multocida makes it a valuable component in SRD treatment protocols.
From the perspective of a manufacturer and supplier, ensuring the quality and consistency of Tylvalosin Tartrate is paramount. Our commitment to high standards, including GMP certification, guarantees a product that performs reliably in treating these conditions. The raw powder form, with its CAS number 63428-13-7, is ideal for formulators looking to develop precise dosages for medicated feeds or water-soluble treatments.
Beyond its antimicrobial action, Tylvalosin Tartrate is noted for its ability to accumulate rapidly in target tissues, providing sustained therapeutic levels. Additionally, when used according to veterinary guidance, it often has no required withdrawal period before slaughter, which is a significant operational advantage for producers. For reliable sourcing and expert support, partnering with a dedicated supplier of veterinary antibiotic raw materials ensures you receive a product that meets your formulation needs and supports the health and productivity of swine operations.
Perspectives & Insights
Bio Analyst 88
“This action disrupts the translation process, halting bacterial growth and reproduction.”
Nano Seeker Pro
“Its efficacy extends to a broad spectrum of pathogens commonly implicated in swine diseases, including Lawsonia intracellularis (the causative agent of PPE), Mycoplasma hyopneumoniae, Pasteurella multocida, and Brachyspira spp.”
Data Reader 7
“Tylvalosin Tartrate is highly effective in controlling this infection, administered typically via feed or drinking water.”