Griseofulvin (CAS 126-07-8): A Comprehensive Guide for Researchers and Formulators
Griseofulvin, identified by its CAS number 126-07-8, is a naturally occurring antibiotic discovered in 1939 from the soil fungus Penicillium griseofulvum. Its pharmacological significance lies in its potent antifungal activity, primarily targeting dermatophyte infections. NINGBO INNO PHARMCHEM CO.,LTD., a leading pharmaceutical intermediate supplier in China, provides high-quality Griseofulvin essential for various medical and research applications.
The mechanism of action for Griseofulvin involves disrupting fungal mitosis by binding to tubulin, thereby inhibiting the formation of the mitotic spindle. This fungistatic effect means it inhibits growth rather than killing the fungi directly, necessitating prolonged treatment courses for complete eradication. Its ability to concentrate in keratinized tissues like skin, hair, and nails is key to its effectiveness against infections such as tinea capitis and onychomycosis. For researchers, understanding these properties is vital when looking to buy Griseofulvin.
Griseofulvin's historical context as one of the first orally effective systemic antifungal agents highlights its importance in medical history. While newer, more targeted antifungals have emerged, Griseofulvin remains relevant, particularly for specific indications and in cases where other treatments are contraindicated or ineffective. Its well-documented safety profile, when used appropriately, further cements its place in therapy. The Griseofulvin price from reliable suppliers reflects its established therapeutic value.
For formulators and researchers, sourcing high-quality Griseofulvin is paramount. NINGBO INNO PHARMCHEM CO.,LTD. in China is a trusted source, offering consistent purity and reliable supply. Our commitment ensures that pharmaceutical companies and research institutions have access to the essential components needed for developing and producing effective treatments. Exploring Griseofulvin options from our extensive catalog provides a gateway to quality pharmaceutical intermediates.
In summary, Griseofulvin (CAS 126-07-8) continues to be a significant compound in the field of antifungal medicine. Its unique mechanism, historical importance, and continued efficacy make it a valuable asset. Partnering with NINGBO INNO PHARMCHEM CO.,LTD. for your Griseofulvin needs means engaging with a quality-focused supplier committed to supporting global health initiatives through reliable chemical provision.
The mechanism of action for Griseofulvin involves disrupting fungal mitosis by binding to tubulin, thereby inhibiting the formation of the mitotic spindle. This fungistatic effect means it inhibits growth rather than killing the fungi directly, necessitating prolonged treatment courses for complete eradication. Its ability to concentrate in keratinized tissues like skin, hair, and nails is key to its effectiveness against infections such as tinea capitis and onychomycosis. For researchers, understanding these properties is vital when looking to buy Griseofulvin.
Griseofulvin's historical context as one of the first orally effective systemic antifungal agents highlights its importance in medical history. While newer, more targeted antifungals have emerged, Griseofulvin remains relevant, particularly for specific indications and in cases where other treatments are contraindicated or ineffective. Its well-documented safety profile, when used appropriately, further cements its place in therapy. The Griseofulvin price from reliable suppliers reflects its established therapeutic value.
For formulators and researchers, sourcing high-quality Griseofulvin is paramount. NINGBO INNO PHARMCHEM CO.,LTD. in China is a trusted source, offering consistent purity and reliable supply. Our commitment ensures that pharmaceutical companies and research institutions have access to the essential components needed for developing and producing effective treatments. Exploring Griseofulvin options from our extensive catalog provides a gateway to quality pharmaceutical intermediates.
In summary, Griseofulvin (CAS 126-07-8) continues to be a significant compound in the field of antifungal medicine. Its unique mechanism, historical importance, and continued efficacy make it a valuable asset. Partnering with NINGBO INNO PHARMCHEM CO.,LTD. for your Griseofulvin needs means engaging with a quality-focused supplier committed to supporting global health initiatives through reliable chemical provision.
Perspectives & Insights
Data Seeker X
“Griseofulvin's historical context as one of the first orally effective systemic antifungal agents highlights its importance in medical history.”
Chem Reader AI
“While newer, more targeted antifungals have emerged, Griseofulvin remains relevant, particularly for specific indications and in cases where other treatments are contraindicated or ineffective.”
Agile Vision 2025
“Its well-documented safety profile, when used appropriately, further cements its place in therapy.”