For veterinarians, livestock producers, and animal health researchers, understanding the efficacy and application of key therapeutic agents is fundamental. Oxyclozanide, a well-established anthelmintic, plays a significant role in combating parasitic diseases in animals. This article provides insight into its mechanism of action and its vital veterinary applications.

Oxyclozanide, known by its CAS number 2277-92-1, is classified as a salicylanilide anthelmintic. Its primary mechanism of action involves disrupting the metabolic processes of parasitic worms, particularly affecting their carbohydrate metabolism. Specifically, Oxyclozanide acts as a proton ionophore, which interferes with oxidative phosphorylation in the mitochondria of parasites. By uncoupling this essential energy-producing pathway, it effectively inhibits ATP synthesis, starving the parasite of energy and leading to its demise.

This mode of action makes Oxyclozanide highly effective against a broad spectrum of parasites, especially nematodes and trematodes. Its utility is most prominently seen in veterinary medicine for the treatment and control of fascioliasis, a liver fluke infestation that commonly affects ruminants such as cattle, sheep, and goats. The low toxicity and low residue profile of Oxyclozanide are significant advantages, ensuring animal safety and minimizing concerns about drug residues in food products.

As a pharmaceutical intermediate and active pharmaceutical ingredient (API), Oxyclozanide is available from manufacturers as a high-purity raw powder. Its consistent quality, typically exceeding 99% purity, ensures reliable therapeutic outcomes when formulated into final veterinary drug products. Companies that buy Oxyclozanide benefit from its proven efficacy in controlling costly parasitic infections that can impact animal health and productivity.

The applications of Oxyclozanide extend beyond fascioliasis. Ongoing research explores its potential in other areas, including its antibacterial and antifungal activities, which further underscore its importance in animal health. Reliable sourcing from experienced manufacturers, particularly those in China, ensures access to this critical veterinary agent. When considering your options to purchase Oxyclozanide, prioritize suppliers who can guarantee quality and provide detailed technical information.

In summary, Oxyclozanide is a potent anthelmintic with a well-defined mechanism of action that targets parasite energy metabolism. Its broad-spectrum efficacy, low toxicity, and established use in treating fascioliasis make it an indispensable tool in veterinary medicine. For those in the industry, securing a dependable supply of high-quality Oxyclozanide is essential for maintaining animal health and agricultural productivity.