Glycine p-Nitroanilide (CAS 1205-88-5) is a molecule of considerable interest in the chemical and biochemical industries, valued for its distinct chemical properties and versatile applications. Understanding its structure, properties, and synthesis provides crucial insights for researchers and procurement specialists looking to buy this compound effectively. Typically presented as a yellow crystalline powder, its chemical characteristics make it a sought-after material for various scientific endeavors.

Chemically, Glycine p-Nitroanilide is an amide derivative formed from glycine and 4-nitroaniline. Its molecular formula is C8H9N3O3, with a molecular weight of approximately 195.18 g/mol. The presence of the nitro group on the aniline ring contributes to its color and its reactivity in certain chemical transformations. Key physical properties often cited include a melting point around 167-172 °C, and solubility in common organic solvents, though specific solubility data can vary. These attributes are critical for any scientist who needs to buy and handle the compound in a laboratory setting.

The synthesis of Glycine p-Nitroanilide typically involves the coupling of glycine or a glycine derivative with 4-nitroaniline. Standard peptide coupling reagents or activation methods can be employed to form the amide bond. Manufacturers often optimize these synthesis routes to achieve high yields and, most importantly, high purity. The purity of Glycine p-Nitroanilide is paramount, especially when it is used as a chromogenic substrate or a pharmaceutical intermediate, as impurities can interfere with enzymatic reactions or subsequent synthetic steps.

A leading Glycine p-Nitroanilide manufacturer will focus on refining the synthesis process to minimize by-products and ensure consistent quality. This commitment to purity, often exceeding 98%, is what differentiates a reliable supplier. For those looking to buy this compound, investigating the manufacturer's synthesis capabilities and quality control procedures is a vital step. The availability of detailed product specifications and Certificates of Analysis from a trusted supplier reassures buyers about the material’s suitability for their intended applications.

In summary, the chemical properties and synthesis of Glycine p-Nitroanilide underscore its importance in fields ranging from biochemistry to medicinal chemistry. By understanding these fundamental aspects, researchers and industry professionals can make informed decisions when sourcing this essential compound, ensuring they buy from a manufacturer that prioritizes quality and provides the technical assurance needed for successful scientific and industrial outcomes.