NINGBO INNO PHARMCHEM CO.,LTD. offers a detailed look into Diphenylphosphine (CAS 829-85-6), an essential organophosphorus compound with a distinct profile of properties, applications, and safety requirements. This colorless liquid, known for its pungent odor, is a critical material in chemical research and industrial synthesis.

The chemical and physical properties of Diphenylphosphine are key to its utility. With a molecular formula of C12H11P and a molecular weight of 186.19, it possesses a boiling point of approximately 280°C. Its sensitivity to air and light, coupled with its pyrophoric nature, necessitates handling under an inert atmosphere, typically nitrogen. This precaution is vital to prevent spontaneous combustion and maintain the compound's integrity for its intended applications.

The primary applications of Diphenylphosphine stem from its role as an intermediate and catalyst precursor. It is extensively used in the synthesis of organophosphine ligands, which are indispensable in homogeneous catalysis. These ligands, when complexed with transition metals, facilitate a wide range of catalytic processes, including asymmetric hydrogenation and various coupling reactions. The ability to tailor ligand structures using Diphenylphosphine allows for fine-tuning catalyst performance for specific reactions, thereby enhancing selectivity and efficiency.

Moreover, Diphenylphosphine is a vital component in the preparation of Wittig-Horner reagents, a class of compounds crucial for forming carbon-carbon double bonds in organic synthesis. This capability makes it a valuable asset in the production of pharmaceuticals, agrochemicals, and advanced materials. Its use in reactions like the Suzuki reaction further underscores its importance in modern synthetic chemistry.

Safety is a paramount consideration when working with Diphenylphosphine. Its pyrophoric nature demands strict adherence to safety protocols, including the use of inert atmosphere techniques for transfer and reaction. NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of consulting the Material Safety Data Sheet (MSDS) and ensuring all personnel are adequately trained in handling pyrophoric materials. By understanding its properties and implementing proper safety measures, Diphenylphosphine can be utilized effectively and securely in various chemical processes.