Cetyl Tranexamate HCl (TXC), a highly effective skin brightening and anti-pigmentation agent, is a valuable addition to advanced cosmetic formulations. As a leading supplier of cosmetic raw materials, NINGBO INNO PHARMCHEM CO.,LTD. provides high-purity TXC and insights into its optimal use. This guide covers key considerations for formulators looking to integrate TXC into their products.

Understanding TXC's Unique Properties for Formulation

TXC's efficacy stems from its improved oil solubility and enhanced skin penetration, 97 times that of traditional tranexamic acid. This oil-soluble nature makes it compatible with the lipid matrix of the skin, facilitating deeper delivery and sustained action. Unlike water-soluble actives, TXC integrates well into oil phases, offering formulators greater flexibility.

Recommended Usage and Concentration

The optimal concentration for TXC in cosmetic products typically ranges from 1% to 3%. For regular whitening and brightening formulations, a concentration of 1-2% is often sufficient to achieve desired results. For targeted treatments, such as spot correctors or products designed for severe hyperpigmentation, concentrations of 3-5% may be employed. It is important for formulators to conduct stability and efficacy testing at their chosen concentration levels, as higher concentrations may lead to skin irritation in some individuals.

Compatibility and Synergistic Effects

TXC demonstrates good compatibility with a wide range of cosmetic actives, allowing for the creation of multi-functional formulations. For enhanced synergistic whitening effects, it is often compounded with ingredients such as:

  • Vitamin C Derivatives: Such as 3-O-ethyl ascorbic acid, which offer antioxidant and brightening benefits.
  • Niacinamide: Known for its barrier-strengthening and anti-inflammatory properties, which complement TXC's actions.
  • Alpha Arbutin and Kojic Acid Dipalmitate: These are powerful melanin inhibitors that can work alongside TXC for more comprehensive pigmentation control.

However, it is advisable to avoid direct mixing with nitrogen-containing active ingredients or certain flavors, as this may lead to instability. Always conduct compatibility testing when formulating with TXC alongside new or sensitive ingredients.

Incorporation and Stability Guidelines

Due to its oil solubility, TXC is best incorporated into the oil phase of a formulation. It is recommended to add TXC at temperatures below 80°C to maintain its integrity. While generally photostable, it is good practice to store formulations containing TXC away from direct sunlight. The optimal pH range for TXC's efficacy is between 5.5 and 7, offering a broad application window for various product types.

Why Source TXC from NINGBO INNO PHARMCHEM CO.,LTD.?

As a premier supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Cetyl Tranexamate HCl is of the highest purity (>99%) and manufactured under strict quality control. We understand the importance of reliable sourcing for formulators. By choosing us, you gain access to competitive pricing, consistent supply, and expert technical support to help you buy and utilize TXC effectively in your groundbreaking cosmetic products.

For formulators looking to buy high-quality TXC and other advanced cosmetic raw materials, we invite you to reach out to us for inquiries and sample requests. Let us be your partner in creating the next generation of effective skincare.