For synthetic organic chemists, the judicious selection of building blocks is fundamental to crafting complex molecules efficiently. 2-Cyclohepten-1-one, identified by CAS number 1121-66-0, is a compelling α,β-enone that offers a unique platform for diverse chemical transformations. This article delves into its synthetic utility and highlights why chemists should consider sourcing it from reliable manufacturers and suppliers.

The Reactivity of an α,β-Enone System

As an α,β-enone, 2-Cyclohepten-1-one possesses two key reactive sites: the carbonyl group and the conjugated double bond. This dual reactivity allows it to participate in a wide array of reactions crucial for building molecular complexity. For instance, the double bond is amenable to conjugate addition reactions, where nucleophiles can be delivered to the β-carbon, a process fundamental in creating new carbon-carbon or carbon-heteroatom bonds. The carbonyl group, conversely, can undergo standard ketone chemistry, such as reductions, nucleophilic additions, and enolate formation. When considering to buy this compound, understanding these inherent reactivities is key to its effective application in your synthetic strategies.

Role in Pharmaceutical Intermediate Synthesis

The pharmaceutical industry heavily relies on versatile intermediates for the synthesis of Active Pharmaceutical Ingredients (APIs). 2-Cyclohepten-1-one serves as an excellent starting material or intermediate in the pathways to numerous complex drug molecules. Its seven-membered ring structure, coupled with the enone functionality, can be elaborated into various heterocyclic systems or chiral centers often found in biologically active compounds. For R&D scientists, sourcing high-purity 2-Cyclohepten-1-one, typically ≥92%, from trusted Chinese manufacturers ensures that their synthetic routes remain robust and reproducible. This intermediate is vital for developing new therapeutics.

Applications in Diagnostic Reagent Development

Beyond pharmaceuticals, 2-Cyclohepten-1-one finds application in the synthesis of specialized molecules used in diagnostic reagents. The precise chemical modifications possible with this enone allow for the creation of probes, labels, or structural components within diagnostic assays. The consistent quality and reliable supply from manufacturers are crucial for the reproducibility of diagnostic tests. When purchasing for such sensitive applications, verifying the CAS number (1121-66-0) and purity is paramount.

Procurement and Handling for Chemists

Chemists looking to buy 2-Cyclohepten-1-one should prioritize suppliers who offer detailed technical specifications and maintain consistent quality. As a liquid that requires refrigerated storage (2-8°C), proper handling and storage are essential to preserve its chemical integrity. Engaging with suppliers who provide comprehensive Safety Data Sheets (SDS) and offer responsive technical support can greatly assist in its effective utilization. For efficient procurement, especially for research quantities or larger scale synthesis, identifying reliable Chinese suppliers can offer a competitive edge in terms of cost and availability.