Cyanidin-3-O-arabinoside chloride, identified by its CAS number 111613-04-8, is a naturally occurring anthocyanin that has garnered considerable scientific interest due to its potent antioxidant capabilities and its potential health benefits. As a member of the flavonoid family, it plays a role in plant defense and is responsible for the vibrant colors in many fruits and flowers. For researchers in the fields of biochemistry, pharmacology, and nutrition, understanding the mechanisms by which this compound exerts its effects is crucial for unlocking its full therapeutic and functional potential.

This article aims to explore the scientific basis of Cyanidin-3-O-arabinoside chloride's antioxidant activity and its implications in various research contexts. We will also provide guidance on sourcing this compound from reliable manufacturers and suppliers, ensuring researchers have access to high-quality materials for their experiments.

Understanding the Antioxidant Mechanisms of Cyanidin-3-O-arabinoside Chloride

The primary mechanism through which Cyanidin-3-O-arabinoside chloride exhibits its antioxidant effects is by neutralizing reactive oxygen species (ROS) and other free radicals. These unstable molecules can cause significant cellular damage, leading to oxidative stress, inflammation, and contributing to the development of chronic diseases such as cardiovascular disease, neurodegenerative disorders, and cancer.

The antioxidant action of Cyanidin-3-O-arabinoside chloride involves several pathways:

  1. Free Radical Scavenging: The phenolic hydroxyl groups present in the cyanidin structure readily donate hydrogen atoms or electrons to unstable free radicals. This process stabilizes the radicals, preventing them from initiating damaging chain reactions within cells.
  2. Metal Chelation: Certain antioxidants can chelate metal ions, such as iron and copper, which can catalyze the formation of ROS. By binding to these metal ions, Cyanidin-3-O-arabinoside chloride can prevent them from participating in Fenton reactions, thereby reducing oxidative damage.
  3. Enzyme Modulation: Research suggests that anthocyanins may also influence endogenous antioxidant defense systems. They can potentially upregulate the activity of enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), which are critical for cellular defense against oxidative stress.
  4. Anti-inflammatory Effects: Oxidative stress and inflammation are closely linked. By reducing ROS levels, Cyanidin-3-O-arabinoside chloride can indirectly exert anti-inflammatory effects, which are of significant interest in the study of inflammatory diseases.

Research Applications and Sourcing from Manufacturers

In scientific research, Cyanidin-3-O-arabinoside chloride (CAS 111613-04-8) is employed in various capacities. It serves as a vital analytical standard for quantifying anthocyanins in natural products. Researchers use it to develop and validate analytical methods, ensuring accuracy in identifying and measuring these bioactive compounds in diverse matrices like berries, red cabbage, and other plant sources.

The compound is also used in in vitro and in vivo studies to investigate its pharmacological effects, including its impact on cellular signaling pathways, mitochondrial function, and disease prevention. For these studies, obtaining high-purity Cyanidin-3-O-arabinoside chloride from a reliable manufacturer is essential. Chinese manufacturers are significant sources for these types of specialized chemicals, often offering competitive pricing and a range of purity grades (e.g., ≥95% or ≥98% HPLC).

When procuring this compound, B2B buyers should prioritize suppliers that provide comprehensive documentation, such as a Certificate of Analysis (CoA), and adhere to strict quality control measures. Understanding the recommended storage conditions (typically below -15°C) is also important to maintain the compound's stability and efficacy for research purposes.

In conclusion, Cyanidin-3-O-arabinoside chloride (CAS 111613-04-8) is a compound of considerable scientific interest due to its potent antioxidant and anti-inflammatory mechanisms. By sourcing high-quality material from reputable manufacturers, researchers can further investigate its potential applications, contributing to advancements in health and nutrition sciences.