In the realm of organic chemistry and industrial manufacturing, understanding the fundamental properties and synthesis of key chemical intermediates is paramount. 2-Chloronitrobenzene, identified by its CAS number 88-73-3, is a compound of significant industrial importance, serving as a precursor in the synthesis of dyes, pharmaceuticals, and agrochemicals. This article aims to provide a comprehensive overview of its chemical characteristics and manufacturing processes, valuable for R&D scientists and production managers.

Chemical Profile of 2-Chloronitrobenzene
2-Chloronitrobenzene is an aromatic organic compound with the chemical formula C6H4ClNO2. It typically presents as yellow crystals and possesses an aromatic odor. Its molecular structure features a benzene ring with a chlorine atom and a nitro group attached at adjacent positions (ortho). This specific arrangement of functional groups makes it highly reactive and suitable for various chemical transformations. Key physical properties include a melting point in the range of 31-33°C and a boiling point of approximately 246°C. Its density is around 1.348 g/mL at 25°C. Understanding these properties is crucial for its safe handling and effective use in synthesis.

Synthesis Routes and Industrial Production
The primary industrial method for producing 2-Chloronitrobenzene involves the nitration of chlorobenzene. This process typically uses a mixture of nitric acid and sulfuric acid. The reaction yields a mixture of isomeric chloronitrobenzenes, predominantly the ortho (2-) and para (4-) isomers, with a smaller amount of the meta (3-) isomer. The ratio of ortho to para isomers can be influenced by reaction conditions, such as temperature and the presence of catalysts like phosphoric acid. While the basic nitration yields a mix, refining and separation techniques are employed to isolate high-purity 2-Chloronitrobenzene, often with purity exceeding 99.0%.

Applications and Industrial Significance
2-Chloronitrobenzene's value lies in its role as an intermediate for producing a wide array of valuable products:

  • Dyes: It is a crucial precursor for synthesizing specific dye intermediates, contributing to the production of vibrant colorants used in textiles and other industries.
  • Agrochemicals: The compound is a building block for various pesticides and herbicides, essential for modern agricultural practices.
  • Pharmaceuticals: It serves as an intermediate in the synthesis of certain active pharmaceutical ingredients (APIs) and related compounds, supporting the healthcare sector.
  • Other Uses: Applications also extend to photographic developers and other specialty chemicals, highlighting its broad utility.

Sourcing and Quality Assurance
For companies seeking to buy 2-Chloronitrobenzene, ensuring high purity and consistent supply is paramount. As a leading manufacturer and supplier in China, we offer 2-Chloronitrobenzene with purity levels often exceeding 99.9%. We adhere to strict quality control measures throughout the production process. For any inquiries regarding pricing, bulk purchases, or to request a sample, please do not hesitate to contact us. Securing a reliable supplier for this essential intermediate is key to your manufacturing success.