For research and development scientists, a deep understanding of chemical intermediates is fundamental to innovation. 2,4,6-Trichloroaniline (CAS 634-93-5) is a versatile compound that finds significant application in organic synthesis, particularly in the creation of complex molecules. This article delves into its key properties, offering insights for researchers aiming to leverage its potential in their projects.

At its core, 2,4,6-Trichloroaniline is an aromatic amine characterized by the presence of three chlorine atoms and an amino group attached to a benzene ring. Its chemical formula, C6H4Cl3N, and a molecular weight of 196.46 g/mol provide the basic structural information. However, for R&D purposes, several physical and chemical properties are of greater immediate importance. The compound typically appears as a colorless to light yellow crystalline powder or liquid, depending on its purity and ambient temperature. A common reported melting point range is 73-75 °C, and a boiling point of approximately 262 °C.

The purity of 2,4,6-Trichloroaniline is a critical factor for successful synthesis. Researchers often require high-purity grades, commonly assaying at 99.0% or higher, to minimize side reactions and ensure reproducible results. When seeking to purchase 2,4,6-Trichloroaniline for laboratory use, it is advisable to look for suppliers that clearly state their purity levels and analytical methods (e.g., HPLC or GC). Reputable chemical manufacturers should provide comprehensive documentation, including detailed specifications and safety data sheets (SDS).

The primary utility of 2,4,6-Trichloroaniline in R&D stems from its reactivity. The amino group can undergo various derivatization reactions, while the chlorine atoms on the aromatic ring can be substituted or involved in coupling reactions. This makes it a valuable building block for:

  • Azo Dye Synthesis: As a diazo component, it contributes to the formation of azo dyes with specific coloristic properties and stability.
  • Agrochemical Development: It serves as a precursor for novel pesticides and herbicides, enabling the design of more effective and targeted crop protection agents.
  • Pharmaceutical Intermediates: In some complex pharmaceutical syntheses, it may be used to introduce specific structural motifs.
  • Material Science: Its chlorinated aromatic structure can be incorporated into polymers or other advanced materials to impart specific properties.

When sourcing this compound, understanding its solubility is also important. While sparingly soluble in water, it is generally soluble in organic solvents like ethanol, ether, and chloroform. This property dictates the choice of reaction media and work-up procedures.

For scientists looking to acquire high purity 2,4,6-Trichloroaniline for their research projects, partnering with a reliable supplier in China can be advantageous. These suppliers often offer competitive pricing and a broad range of research-grade chemicals. It is always recommended to request a sample to verify its suitability for your specific application before placing a bulk order. Engaging with a knowledgeable manufacturer can also provide valuable technical support regarding handling and reaction optimization.

In summary, the key properties of 2,4,6-Trichloroaniline – its structure, purity, reactivity, and solubility – make it a vital tool for synthetic chemists. By carefully considering these aspects when looking to buy 2,4,6-Trichloroaniline, R&D professionals can ensure the success of their innovative projects.