The pharmaceutical industry constantly seeks high-quality, reliable intermediates to build complex drug molecules. 4-Aminobenzamide, known by its CAS number 2835-68-9, is one such compound that has garnered significant attention due to its versatility in synthetic pathways. For pharmaceutical researchers, development scientists, and procurement managers, understanding its properties and sourcing options is key to successful drug discovery and manufacturing.

The Chemical Backbone: Properties of 4-Aminobenzamide

Typically supplied as a white crystalline powder with a purity assay of 99.5% or higher, 4-Aminobenzamide boasts a melting point in the range of 182-184°C. These characteristics are crucial for pharmaceutical synthesis, where precise chemical structures and high purity are non-negotiable. The consistent nature of these physical and chemical properties ensures predictable reactions and simplifies the validation processes required in pharmaceutical development.

4-Aminobenzamide's Role in Drug Development

As a synthetic intermediate, 4-Aminobenzamide serves as a valuable building block in the creation of various active pharmaceutical ingredients (APIs). Its amine and amide functional groups allow for a range of chemical modifications, making it adaptable for diverse synthesis routes. Pharmaceutical companies looking to buy 4-Aminobenzamide are typically focused on its ability to contribute to the development of novel therapeutics. Its application spans different therapeutic areas, making it a versatile component in the chemist's toolkit.

For R&D departments, access to this intermediate can be critical for:

  • Exploring New Molecular Entities: The compound's structure can be a starting point for designing and synthesizing new drug candidates.
  • Optimizing Synthesis Routes: Its reactivity profile might offer more efficient or cost-effective pathways to known APIs compared to alternative intermediates.
  • Ensuring API Purity: Using high-purity 4-Aminobenzamide as a starting material contributes to the overall purity of the final API, a critical factor in drug safety and efficacy.

Strategic Sourcing for Pharmaceutical Needs

Procurement managers in the pharmaceutical sector face the challenge of sourcing intermediates that meet rigorous quality standards while remaining cost-effective. Manufacturers in China are often a primary source for chemicals like 4-Aminobenzamide due to their large-scale production capabilities and competitive pricing. When considering a purchase, it is essential to partner with suppliers who can provide:

  • Certifications: Ensuring compliance with relevant industry standards.
  • Traceability: A clear chain of custody for the material.
  • Comprehensive Documentation: Including Certificates of Analysis (CoA) and detailed Safety Data Sheets (SDS).
  • Reliable Delivery: Consistent supply to prevent disruptions in manufacturing schedules.

By diligently evaluating potential suppliers and understanding the critical quality parameters of 4-Aminobenzamide, pharmaceutical companies can secure a consistent and high-quality supply of this vital intermediate, thereby supporting their ongoing drug development and manufacturing efforts.